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2-Amino-5-Bromopyridine (CAS 1072-97-5)

  • Surfactant Appearance: powder
  • Proportion: Minimum 99.0%
  • Inventory: In stock
  • Sample: In stock
  • Zhishang Chemical: Supplier and manufacturer of 2-Amino-5-Bromopyridine

Basic Info of 2-Amino-5-Bromopyridine

Technical ParameterGuaranteed Specification
Chemical Name2-Amino-5-bromopyridine (5-Bromopyridin-2-amine)
CAS Registry NumberCAS 1072-97-5
Molecular Formula / WeightC5H5BrN2 / 173.01 g/mol
Purity (HPLC)≥ 98.0% (Assay)
AppearanceWhite to off-white or light brown crystalline powder
Melting Point135.0°C - 138.0°C
Water Content (Karl Fischer)≤ 0.5%
Certifications & AnalyticsISO 9001:2015, Batch COA, HPLC, H-NMR, MSDS

What is 2-Amino-5-Bromopyridine?

Product Properties

 

2-Amino-5-bromopyridine (CAS 1072-97-5), also structurally designated as 5-bromopyridin-2-amine, is a highly pure heterocyclic building block and functionalized halogenated pyridine derivative. Exhibiting a molecular formula of C5H5BrN2 and a molecular weight of 173.01 g/mol, this compound typically presents as a white, off-white, to pale brown crystalline powder with a distinct melting range of 135.0°C to 138.0°C.

Characterized by the strategic co-existence of an electron-donating amino group and an electrophilic bromine substituent on its pyridine core, it demonstrates excellent chemical reactivity in cross-coupling pathways. The substance is soluble in common organic solvents such as dimethyl sulfoxide (DMSO), methanol, and dichloromethane. Manufactured to strict quality standards, our product maintains a guaranteed HPLC purity of ≥98.0% and moisture content under 0.5%, ensuring superior thermal stability and analytical reliability for multi-step organic synthesis.

2-Amino-5-bromopyridine Applications & Uses

 

  • Pharmaceutical Intermediate & API Synthesis

    It serves as a critical pharmaceutical intermediate and core precursor for synthesizing active pharmaceutical ingredients (APIs). Due to its reactive bromine and amino positions, it is widely utilized in medicinal chemistry to construct targeted kinase inhibitors, antibacterial agents, and novel heterocyclic drugs in clinical and commercial R&D pipelines.

  • Organic Cross-Coupling & Chemical Building Block

    Functions as a versatile fine chemical building block in modern organic chemistry laboratories. It is routinely deployed in key catalytic reactions—including Suzuki-Miyaura cross-coupling, Buchwald-Hartwig amination, and Sonogashira coupling—to assemble complex biaryl systems and customized organic molecules.

  • Agrochemical & Specialty Chemical Manufacturing

    Acts as an important chemical intermediate in the custom synthesis of novel crop protection compounds, advanced agrochemicals, and specialized functional materials, offering stable reaction yields for CRO, CDMO, and industrial chemical producers globally.

Product Packaging

If you want to buy 2-Amino-5-Bromopyridine, pls contact us to get a free quote.​

Superior 2-Amino-5-Bromopyridine Series | Reliable Quality & Sufficient Supply

Sourcing critical fine chemicals presents operational bottlenecks for purchasing managers, including batch-to-batch variation, uncontrolled brominated byproducts, and unexpected lead-time delays. Supplying sub-standard 2-amino-5-bromopyridine CAS 1072-97-5 risks synthesis failure, costly downstream purification, and missed project deadlines.

We eliminate these risks through engineered process chemistry, scalable infrastructure, and absolute quality assurance.

Our synthesis utilizes an optimized regioselective bromination process combined with temperature-controlled catalytic pathways, ensuring high step-yields while suppressing isomer impurities. Refining is carried out via precision multi-stage recrystallization, maintaining heavy metals below 10 ppm and single unassigned impurities under 0.5%.

Operating within an ISO 9001:2015 certified quality management system, our facility boasts a robust monthly production capacity exceeding 1,000 kg, supported by a standing ready-to-ship safety stock of 100 kg to 300 kg.

Real-World Case Study:

A North American biotechnology firm experienced yield drops (under 62%) in their heterocyclic coupling sequence due to batch variability from a previous vendor. Upon switching to our batch-certified 2-amino-5-bromopyridine (HPLC purity 98.6%, water content <0.3%), their reaction yield stabilized at 89% over 8 consecutive production runs, reducing overall raw material validation costs by 18%. Every order is shipped with complete analytical support, including batch-specific COA, HPLC traces, H-NMR spectra, and SDS documentation.

Supply Plans & Delivery Timelines

To ensure seamless procurement continuity, we offer flexible supply arrangements tailored to both small-scale laboratory testing and commercial-scale manufacturing schedules:

  • R&D & Pilot Scale Orders (100g – 5kg): Samples and trial orders are dispatched within 24 to 48 hours directly from our ready-to-ship inventory via express carriers (DHL, FedEx, UPS). Estimated transit time is 3 to 5 business days worldwide.

  • Commercial Scale Procurement (50kg – 500kg): Orders are fulfilled within 7 to 10 business days. Custom light-resistant, moisture-proof drum packaging is prepared alongside full export documentation.

  • Contract Manufacturing & Long-Term Supply Contracts (> 1,000kg): Scheduled batch production programs can be established with reserved workshop capacity, guaranteeing locked-in pricing and staggered monthly shipments according to your supply chain timeline.

  • Logistics & Compliance: All shipments are packed in air-tight UN-approved fiber drums with inner double PE bags. We collaborate with accredited dangerous goods (DG) freight forwarders to provide air and ocean transport with compliant MSDS and customs documentation.

FAQ

Our 2‑Amino‑5‑bromopyridine is supplied at a guaranteed purity of ≥98.0% (HPLC). Every shipment includes batch‑specific analytical documentation, including a Certificate of Analysis (COA), High‑Performance Liquid Chromatography (HPLC) spectrum, H‑NMR spectrum, and Safety Data Sheet (SDS).

Yes, with a monthly production capacity exceeding 1,000 kg and regular stock between 100 kg and 300 kg, small to medium orders (up to 50 kg) ship within 24‑48 hours. Large commercial orders (100 kg‑500 kg) are delivered within 7 to 10 business days.

We operate under ISO 9001:2015 standards. Our controlled regioselective synthesis and multi‑stage recrystallization limit single impurities to <0.5% and water content to <0.5%. Every batch undergoes double verification by internal quality control before packaging.

We offer R&D sample bottles (100g, 500g, 1kg) and bulk commercial packaging in 25kg fiber drums lined with double PE moisture‑proof bags. All packaging conforms to international air and sea freight safety standards for chemical transport.

If internal testing reveals that the delivered material does not conform to agreed specifications outlined in our COA, our technical support team provides a free replacement or 100% refund policy within 30 days following joint technical review.

References

The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.

Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.

2-Amino-5-Bromopyridine Supplier and Manufacturer

As a 2-Amino-5-Bromopyridine supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best 2-Amino-5-Bromopyridine raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for 2-Amino-5-Bromopyridine and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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