Zhishang Bio Technology|Supplier of pharmaceutical intermediates, pesticide intermediates and cosmetics raw materials

PRODUCT

2-Amino-5-nitrothiazole

2-Amino-5-nitrothiazole CAS 121-66-4

CAS:121-66-4 | C3H3N3O2S |MW:145.14 | EINECS NO:204-490-9

Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union

Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP

Transporta: Ocean, Land,Air, DHL,TNT

Port: Shanghai Port, Qingdao Port

Description

The most common form of 2-Amino-5-nitrothiazole is a yellow to brownish yellow powder or crystalline powder. The main source of color is the nitro group, which can absorb visible light to appear yellow. Status: Fine, dry powder. 2-Amino-5-nitrothiazole is slightly soluble or insoluble in water. In polar organic solvents, it is typically moderately or highly soluble. It has a very clear melting point which is a physical constant that is commonly used to determine purity. The melting point of high purity samples can be lower. Under normal temperature, dry, and dark conditions, 2-Amino-5-nitrothiazole is usually stable. Due to the presence of electron-rich thiazole rings and nitro groups, 2-Amino-5-nitrothiazole may be sensitive to strong acid/base conditions, strong oxidizing agents and strong reducing agents. 2-Amino-5-nitrothiazole should be sealed and stored in a cool, dry, and dark place, usually in brown glass bottles or buckets lined with plastic bags to reduce the impact of light and moisture.

Product Images & Packaging

2-Amino-5-nitrothiazole
2-Amino-5-nitrothiazole
2-Amino-5-nitrothiazole

Product Parameters

2-Amino-5-nitrothiazole Chemical Properties
Melting point 195-200 °C (dec.) (lit.)
Boiling point 345.1±15.0 °C(Predicted)
density 1.583 (estimate)
refractive index 1.6740 (estimate)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility 95% ethanol: soluble1g/150g at 20°C
form Powder
pka1.26±0.10(Predicted)
color Yellow
Water Solubility <0.1 g/100 mL at 20 ºC
Sensitive Light Sensitive
Merck 14,457
BRN 126797

The application of 2-Amino-5-nitrothiazole

1. Intermediates for pharmaceutical synthesis

This is the primary and most widespread use of 2-Amino-5-nitrothiazole. Its structure is a core skeleton for many pharmacologically active molecules.

It is a precursor to a number of nitroimidazole- and nitrothiazole-based drugs. It is the most popular example for synthesizing antibacterial, anaerobic and antiparasitic drugs with broad spectrum, such as metronidazole.

The nitro groups in the pathogen are reduced to produce cytotoxic substances.

As a key building block, 2-Amino-5-nitrothiazole is also used in the development and synthesis of other types of drugs, such as anti ulcer drugs, anti-tumor drug candidate compounds, and anti-inflammatory drugs.

2. Intermediates for the Synthesis of Agricultural Chemicals

In the field of agricultural chemicals, 2-Amino-5-nitrothiazole is used to manufacture highly efficient pesticides.

Synthetic insecticides & acaricides : Through further chemical modification of amino and thiazole rings it is possible to develop insecticides & acaricides that have specific biological activity for protecting crops.

Synthetic fungicide: The structure of 2-Amino-5-nitrothiazole has inhibitory effects on certain plant pathogens, making it a starting material for synthesizing new fungicides.

3. Industry of dyes and pigments

The nitro group in the 2-Amino-5-nitrothiazole molecule is a strong chromophore, and the amino group is a chromophore. Both can be combined with the thiazole rings to produce rich colors.

Synthesis of Disperse Dyes and Azo Dyes: 2-Amino-5-nitrothiazole can be used as a diazo component or coupling component for the production of yellow, orange to red series dyes and pigments. These dyes can be used to dye synthetic fibers.

4. Chemical Research and Analysis

It is used in academic research as well as fine chemical development. Amino groups are capable of acylation, Alkylation, and other reactions. Nitro groups can also be reduced to amino group, which opens up more possibilities for reaction.

Analytical reagents: In certain specific chemical analyses, 2-Amino-5-nitrothiazole may be used as a chelating reagent for detecting or quantifying certain metal ions.

2-Amino-5-nitrothiazole 's Procurement Guide

Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)

2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ:1kg

3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services

Paeonol

FAQ

Yes, we have our own factory called ” ZhiShang Industry Group “

Yes, we have GMP certificate for some products, and we can provide DMF as well.

 -Quality you require, eg. Assay, Purity, or single impurity

-Quantity you need

-Standard you want, such as USP, EP, JP etc.

Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well.

For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment. 

For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 day.

Related References

Pubchem-2-Amino-5-nitrothiazole

Manufacturer of 2-Amino-5-nitrothiazole

Company Info

Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
 
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.

Hot Products

Scroll to Top

Contact us to Get COA

Contact us to Get MSDS