2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (CAS 1013916-37-4): A Comprehensive Product Introduction
Overview
2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (CAS 1013916-37-4) is a chemical compound that has attracted significant attention in the scientific and industrial communities. This compound belongs to the class of pyrido[2,3-d]pyrimidin-7-ones, which often exhibit diverse biological activities and potential applications in various fields. In this article, we will explore the properties, uses, applications, and preparation methods of 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one in detail.
Physical and Chemical Properties
The physical and chemical properties of 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one are crucial for understanding its behavior and potential applications. This compound has a specific molecular formula, which determines its chemical structure and reactivity. The presence of the chlorine atom, cyclopentyl group, and methyl group on the pyrido[2,3-d]pyrimidin-7-one core structure gives it unique chemical characteristics.
It has a certain melting point, boiling point, and solubility in different solvents. These properties are important for its purification, formulation, and use in various processes. For example, the solubility of the compound in organic solvents can affect its extraction and separation methods during the preparation process. The melting point and boiling point can also influence its handling and storage conditions.
Biological Activities
One of the most interesting aspects of 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one is its potential biological activities. Many compounds in the pyrido[2,3-d]pyrimidin-7-one class have been reported to exhibit anti – cancer, anti – inflammatory, and antibacterial properties. This compound may interact with specific biological targets in cells, such as enzymes or receptors, to modulate biological processes.
For anti – cancer activity, it may inhibit the growth of cancer cells by interfering with their cell cycle progression or inducing apoptosis. In the case of anti – inflammatory activity, it could block the production of inflammatory mediators, reducing the inflammatory response in the body. Antibacterial activity might involve disrupting the cell membrane or metabolic pathways of bacteria.
Uses and Applications
Pharmaceutical Industry
In the pharmaceutical industry, 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one serves as a valuable building block for the synthesis of new drugs. Medicinal chemists can modify its structure to design and develop novel therapeutic agents with improved efficacy and fewer side effects. For example, by attaching different functional groups to the core structure, they can create compounds that target specific diseases more precisely.
It can also be used in pre – clinical research to study the biological mechanisms of action. Researchers can use this compound to investigate how it interacts with biological molecules in the body, which helps in understanding the pathogenesis of diseases and developing new treatment strategies.
Agrochemical Industry
In the agrochemical industry, this compound may have potential applications as a pesticide or fungicide. Its chemical structure and biological activities may allow it to control pests or fungi that damage crops. For example, it could act on the nervous system of pests or inhibit the growth of fungal mycelium, protecting plants from diseases and pests.
Moreover, it can be used in the development of new agrochemical formulations. By combining it with other active ingredients or adjuvants, more effective and environmentally friendly agrochemical products can be created.
Materials Science
In materials science, 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one can be used in the synthesis of functional materials. For example, it can be incorporated into polymers to modify their properties, such as improving their thermal stability, mechanical strength, or electrical conductivity. These functional polymers can be used in various applications, including electronics, packaging, and coatings.
Preparation Methods
Chemical Synthesis Routes
There are several chemical synthesis routes available for the preparation of 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one. One common approach is to start from appropriate starting materials and carry out a series of chemical reactions, including condensation, cyclization, and substitution reactions.
For example, a suitable pyridine derivative can be reacted with a cyclopentylamine and a methylating agent to form an intermediate. Then, a chlorination reaction can be carried out to introduce the chlorine atom at the desired position. The reaction conditions, such as temperature, reaction time, and the choice of solvents and catalysts, need to be carefully optimized to achieve high yields and purity of the final product.
Purification and Isolation
After the synthesis, the crude product needs to be purified and isolated. This can be achieved through various methods, such as column chromatography, recrystallization, and extraction. Column chromatography is a commonly used method, which separates the product from impurities based on their different affinities for the stationary phase. Recrystallization can further purify the product by dissolving it in a suitable solvent and then allowing it to crystallize out under controlled conditions.
Safety and Handling
When handling 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one, appropriate safety measures should be taken. It is recommended to wear protective clothing, gloves, and goggles to avoid direct contact with the compound. In case of inhalation, ingestion, or skin contact, immediate medical attention should be sought.
The compound should be stored in a cool, dry place away from sources of heat and ignition. It should be kept in a well – sealed container to prevent its degradation and contamination.
References
- [1] Some research paper on pyrido[2,3-d]pyrimidin-7-ones. Link to the paper
- [2] Another study related to the synthesis of 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one. Link to the study