PRODUCT
Zhishang Bio 2-Methyl-5-nitroaniline CAS 99-55-8
CAS:99-55-8 | C7H8N2O2 |MW：152.15 | EINECS NO：202-765-8
Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Transporta: Ocean, Land,Air, DHL，TNT
Port: Shanghai Port, Qingdao Port
Description
The Chemical Essence and Structure of 2-Methyl-5-nitroaniline
2-Methyl-5-nitroaniline is an important aromatic amino nitro compound, which has both amino (- NH ₂) and nitro (- NO ₂) functional groups attached to a benzene ring in toluene.
Its chemical formula can be written as C ₇ H ₈ N ₂ O ₂, and the system name clearly indicates the position of the substituent: the amino group is located adjacent to the methyl group, and the nitro group is located at the para position of the methyl group. The specific relative position between this adjacent amino group and the para nitro group profoundly affects its physical and chemical properties as well as reaction activity.
Physical and Chemical Properties of 2-Methyl-5-nitroaniline
2-Methyl-5-nitroaniline is typically a yellow to orange yellow or yellow brown crystalline or crystalline powder, which is a typical color of aromatic nitro compounds.
It is slightly soluble in cold water, soluble in hot water, easily soluble in organic solvents such as ethanol, ether, benzene, chloroform, and can dissolve in inorganic acids to form salts. The melting point is in the range of 107-110 ° C. From a chemical perspective, its molecules possess both the alkalinity and nucleophilicity of aromatic primary amines, as well as the strong electron withdrawing and reducibility of aromatic nitro groups.
Chemical properties of 22-Methyl-5-nitroaniline
2-Methyl-5-nitroaniline, as an aromatic primary amine, undergoes a typical diazotization reaction with its amino group to generate the corresponding diazonium salt, which is its most important reaction as a dye intermediate. Amino groups can also undergo acylation, alkylation, and other reactions.
Nitro is a strong electron withdrawing group that reduces the activity of electrophilic substitution reactions at other positions on the benzene ring and affects the alkalinity of the amino group. Meanwhile, nitro groups can be reduced to amino groups under specific conditions, generating ortho methyl p-phenylenediamine, thereby providing additional reaction sites.
Adjacent amino groups and methyl groups may exhibit certain steric hindrance effects.
Product Images & Packaging
Product Parameters
| 2-Methyl-5-nitroaniline Chemical Properties |
| Melting point | 103-106 °C(lit.) |
| Boiling point | 294.61°C (rough estimate) |
| density | 1.2333 (estimate) |
| refractive index | 1.6276 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 2.34±0.10(Predicted) |
| color | Ochre to yellow-orange |
| Water Solubility | <0.1 g/100 mL at 19 ºC |
| BRN | 879021 |
| Exposure limits | ACGIH: TWA 1 mg/m3 |
| Stability: | Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, acids, chloroformates. |
The application of 2-Methyl-5-nitroaniline
1.Main application of dye intermediates
This is the most traditional and primary application area of 2-Methyl-5-nitroaniline， used for synthesizing various important azo dyes and disperse dyes.
2-Methyl-5-nitroaniline can undergo diazotization reaction to generate the corresponding diazonium salt. As a key coupling agent, this diazonium can undergo coupling reaction with various coupling components to produce azo compounds that have larger molecular masses and longer conjugated system. The azo dyes are available in many bright colors, including yellow, orange, red, and blue. They can be used for textiles, leathers and papers as well as ink.
2-Methyll-5-nitroaniline itself is an important precursor for the synthesis of certain azo based dispersed dyes. Dispersed dye molecules for dyeing polyester or synthetic fibers can be created by protecting the amino group, diazotizing, or reducing its nitro group. These dyes are bright and have excellent color fastness.
2. Use as a pigment intermediary
This pigment can be further converted to organic pigments with better performance by chemical conversion.
Starting from 22-Methyl-5-nitroaniline， high-performance organic pigments with more complex molecular structures, better thermal stability, and weather resistance can be synthesized through diazotization, coupling, and possible further reactions such as ring closure and acylation. This pigment is bright, has a strong coverage and is resistant against sunlight and migration. This pigment is used for advanced coatings, printing inks and plastic coloring.
3.Applications for the Synthesis of Pharmaceutical and pesticide Intermediates
The chemical activity of different substituents on the benzene ring of 2-Methyl-5-nitroaniline makes it a useful building block for constructing complex heterocyclic molecules.
Amino and nitro groups are functional chemical groups. They can undergo a variety of reactions, such as acylations, alkylations, and reductions. Therefore, 2-Methyl-5-nitroaniline can be used as an intermediate for the synthesis of certain drugs containing benzoheterocyclic structures, for constructing the core skeleton of drug molecules.
Similarly, the 2-methyl-5-nitroaniline structure also exists in the design of certain pesticide molecules. It can be used in a series reactions to synthesize intermediates for insecticides and herbicides that have specific biological activity, providing a chemical base for pesticide innovations.
2-Methyl-5-nitroaniline 's Procurement Guide
Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)
2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ：1kg
3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services
FAQ
Yes, we have our own factory called ” ZhiShang Industry Group “
Yes, we have GMP certificate for some products, and we can provide DMF as well.
-Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well.
For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 day.
Related References
Pubchem-2-Methyl-5-nitroaniline
Manufacturer of 2-Methyl-5-nitroaniline
Achievements
Advantage
Service
FAQ
Advice on Shipping
Achievements
Zhishang Bio is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang Bio will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 2-Methyl-5-nitroaniline manufacturer, Zhi shang Bio has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Advantage
Zhishang Bio is a professional enterprise engaged in the research and development, production, and sales of chemical raw materials. It has a strong supply chain system and strict quality control standards to ensure the provision of high-quality products with high purity and stability to customers.
Zhishang Bio’s core strength is its independent research and design capabilities. It has advanced production equipment, testing laboratories and can customize chemical raw materials to meet the market demands. This includes pharmaceuticals, electronic, coatings and agricultural applications.
Zhishang Bio’s supply chain management is based on long-term relationships with domestic and international suppliers of high quality to guarantee a stable supply, optimize logistic systems, and achieve efficient distribution. This helps reduce the cost of customer purchases.
We adhere to international environmental standards and we also adhere to the concept that environmental protection and safety production are important. All production processes must comply with these standards in order to guarantee that our products will be green and sustainable.
With a professional technical team and comprehensive after-sales service, Zhishang Bio can provide customers with precise technical support, solve application problems, and help customers enhance product competitiveness.
We are always customer-oriented and committed to becoming a trusted chemical raw material partner.
Service
Zhishang Biography is dedicated to using clients extensive and expert service, including chemical raw material. The customers will certainly receive hassle-free, efficient and one-stop options.
1. Custom-made Supply Solutions
Zhishang Bio provides tailored services for clients in the chemical basic material sector, including special bit dimension, solvent residue control, stability optimizations and more. Clients can personalize their services to satisfy details requirements in industries such as drugs, electronic devices, and finishings.
2. Strict quality assurance
Zhishang Bio utilizes advanced screening equipment and stringent quality examination procedures, in addition to various other files, to guarantee that every batch of products is certified with international criteria such ISO GMP, REACH, and so on. Customers are also given with full quality records and conformity documents.
The supply chain is secure
Zhishang Bio has actually established lasting calculated collaborations with worldwide makers of top notch raw materials to make certain a secure supply, maximize the storage facility and logistics system, and assistance both small-scale examinations and large orders. It adjusted to the changing requirements of clients by responding flexibly to these changes.
4. Technical support
Zhishang Bio’s technical group can offer suggestions on product applications, formula optimization and analysis of industry patterns to aid clients fix technological troubles during production and boost item efficiency.
5. Efficient after-sales service
Zhishang Bio provides complete monitoring, reacts to client requests and delivers promptly. This will certainly make certain customer complete satisfaction.
Zhishang Biography intends to help consumers expand their service by providing the very best solutions and chemical resources.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.
