Zhishang Bio Technology|Supplier of pharmaceutical intermediates, pesticide intermediates and cosmetics raw materials

PRODUCT

3-Methoxybenzonitrile

3-Methoxybenzonitrile CAS 1527-89-5

CAS:1527-89-5 | C8H7NO |MW:133.15 | EINECS NO:216-201-3

Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union

Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP

Transporta: Ocean, Land,Air, DHL,TNT

Port: Shanghai Port, Qingdao Port

Description

3-Methoxybenzonitrile, As an important organic chemical intermediate and fine chemical, it usually appears as a white to off white crystalline solid or powder at room temperature and pressure, with a pure appearance and presenting a regular morphology unique to crystalline substances. 3-Methoxybenzonitrile has a significant aromatic odor, which is characterized by its benzene ring structure, but the specific odor may vary depending on purity. In terms of physical properties, the melting point range of 3-methoxybenzonitrile is relatively clear, approximately between 38 and 42 degrees Celsius, which means that at slightly higher room temperatures or summer conditions, it may begin to soften or even melt into a colorless to pale yellow oily liquid. This is due to its hydrophobic molecular structure. However, it is soluble in a variety of organic solvents, including methanol and ethanol. This property makes it easy to use and can be used in organic synthesis. It contains two functional groups that are important from a chemical perspective: methoxy, and cyano. Methoxy is the electron donating group that affects the electron cloud distribution of the benzene ring, giving 3-Methoxybenzonitrile specific regioselectivity in electrophilic substitution reactions; The cyano group is a highly polar electron withdrawing group with high reactivity, which can be converted into various other functional groups such as amides, carboxylic acids, or amines. This is the main value of this intermediate as a synthesizer. Due to the presence of the cyanide group in the molecular structure of 3-Methoxybenzonitrile, there is a risk of combustion when exposed to open flames and high temperatures, and it may decompose and produce toxic hydrogen cyanide gas under specific conditions. It is important to store it away from heat and fire sources. The container should also be sealed and kept in a cool and ventilated place.

Product Images & Packaging

3-Methoxybenzonitrile
3-Methoxybenzonitrile
3-Methoxybenzonitrile

Product Parameters

3-Methoxybenzonitrile Chemical Properties
Melting point 20-22°C
Boiling point 111-112 °C13 mm Hg(lit.)
density 1.089 g/mL at 25 °C(lit.)
refractive index n20/D 1.5402(lit.)
Fp 221 °F
storage temp. Sealed in dry,Room Temperature
Water Solubility Slightly soluble in water
form powder to lump to clear liquid
color White or Colorles to Yellow to Orange
BRN 1932666
InChIInChI=1S/C8H7NO/c1-10-8-4-2-3-7(5-8)6-9/h2-5H,1H3

The application of 3-Methoxybenzonitrile

3-Methoxybenzonitrile, With the presence of two key reactive sites, methoxy and cyano, in its molecular structure, it plays an extremely important role as a multifunctional intermediate in the field of organic synthesis, with a wide range of applications spanning multiple fine chemical branches such as medicine, pesticides, and materials science. Firstly, in the field of pharmaceutical research and synthesis, 3-methoxybenzonitrile is an indispensable cornerstone molecule. The methoxy group of the benzene rings can be an important pharmacophore. It is directly present in the final drug molecules, and it affects the solubility, metabolism stability, as well as the interaction with the target. The cyanide functional group can be converted into other functional groups by simple chemical reactions. This allows for the construction of complex drug molecules. The cyano group can be hydrolyzed to amides, carboxyl groups or peptide bonds. Therefore, 3-methoxybenzonitrile is often used as a starting material or intermediate for the synthesis of a series of active pharmaceutical ingredients such as analgesics, antidepressants, antihypertensive drugs, and nonsteroidal anti-inflammatory drugs. Secondly, in the field of pesticide chemistry, the application of 3-methoxybenzonitrile is equally crucial. Many efficient herbicides, fungicides, and insecticides contain phenyl ether or benzoate ester structures in their molecular structures, and 3-methoxybenzonitrile is an ideal precursor for constructing these structures. Through a series of derivatization reactions between cyanide and methoxy groups, pesticide chemists can synthesize new compounds with specific biological activity. It can be used, for example, to synthesize certain herbicides based on phenoxycarboxylic acids, or as the key fragment in the synthesis of pyrazole- and triazole-based high-efficiency fungicides that play a vital role in protecting and increasing agricultural yields. In addition, in the field of polymer materials and functional chemicals, 3-methoxybenzonitrile has also demonstrated its unique value. The cyan groups can be used as polar monomers in polymerization reactions or as modifiers. They are also involved in the synthesis polyamides or polyesters or polyurethanes. It is also used as an intermediate for the synthesis certain pigments and dyes. The electron-donating effect of methoxy can control the conjugated system of molecules and their light absorption properties, thus affecting the color. In the development of liquid crystal materials, molecules containing cyanobiphenyl or phenyl ether structures are common liquid crystal units, and 3-methoxybenzonitrile provides the basic building block for the preparation of such advanced electronic materials.

3-Methoxybenzonitrile 's Procurement Guide

Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)

2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ:1kg

3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services

Paeonol

FAQ

Yes, we have our own factory called ” ZhiShang Industry Group “

Yes, we have GMP certificate for some products, and we can provide DMF as well.

 -Quality you require, eg. Assay, Purity, or single impurity

-Quantity you need

-Standard you want, such as USP, EP, JP etc.

Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well.

For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment. 

For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 day.

Manufacturer of Magnesium Hydroxid

Company Info

Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
 
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.

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