4-Aminophenol CAS 123-30-8 Supplier | 98% purity | Zhishangbio
Zhishang Bio 4-Aminophenol CAS 123-30-8
CAS:123-30-8 | C6H7NO |MW：109.13 | EINECS NO：204-616-2
Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Transporta: Ocean, Land,Air, DHL，TNT
Port: Shanghai Port, Qingdao Port
4-Aminophenol Description
Technical Overview: 4-Aminophenol (CAS 123-30-8)
4-Aminophenol (CAS 123-30-8), chemically structured as p-aminophenol with the molecular formula C₆H₇NO, functions as a highly reactive bifunctional intermediate bridging the pharmaceutical and fine chemical sectors. Synthesis engineers track this 109.13 MW crystalline matrix primarily for its role as the irreplaceable precursor in commercial manufacturing loops for paracetamol (acetaminophen).
Beyond baseline analgesics, it serves as a foundational building block for complex APIs like Acebutolol, Ambroxol, and Sorafenib. Physically, this light-sensitive substance presents as a white to cream crystalline powder with a sharp melting threshold of 188°C. Because its chemical structure carries a pKa of 5.48 and 10.30, alkaline solutions of this molecule oxidize rapidly, requiring strict atmospheric protection inside your processing vessels.
Clean Catalytic Hydrogenation Production Line
[Nitrobenzene Raw Feedstock] + [Noble Metal Catalyst Bed] ➔ [Single-Step Catalytic Hydrogenation] ➔ [Low-Moisture Crystallization] ➔ [Pure 4-Aminophenol ≥98%]
The workflow matrix above maps our optimized, eco-friendly synthesis sequence. By replacing old iron-acid reduction setups, this vapor-phase catalytic loop cuts down on heavy waste streams while maintaining the following batch release metrics:
| Analytical Parameter | Checked Value Profile | Operational Benefit |
|---|---|---|
| Active Titration Purity | ≥ 98.00% (validated by GC) | Protects downstream catalyst life |
| Moisture Content Cap | ≤ 0.50% (Karl Fischer) | Minimizes side reactions and caking |
| Residue on Ignition | ≤ 1.00% | Ensures clear solution clarity |
Product Images & Packaging
4-Aminophenol Parameters
| 4-Aminophenol Chemical Properties |
| Melting point | 188 °C |
| Boiling point | 284 °C |
| density | 1.29 |
| vapor pressure | 0.4 hPa (110 °C) |
| refractive index | 1.5444 (estimate) |
| Fp | 189 °C |
| storage temp. | 2-8°C |
| solubility | water: slightly soluble |
| form | Crystalline Powder |
| pka | 5.48, 10.30(at 25℃) |
| color | White to cream |
| Water Solubility | 1.5 g/100 mL (20 ºC) |
| Sensitive | Air & Light Sensitive |
| Decomposition | 284 °C |
| Merck | 14,462 |
| BRN | 385836 |
Why Partner with Zhishang Bio?
1. Massive 10,000-Ton Output & Secured Spot Buffers
We shield your processing plant from sudden raw material shortages by maintaining a constant inventory buffer of standard 25kg multi-wall bags at our regional fulfillment hubs. Our production partners operate massive 220,000 m² facilities backed by 27 years of primary refining experience, delivering a steady annual capacity exceeding 10,000 metric tons.
This massive scale ensures you completely bypass market procurement bottlenecks. Whether your current manufacturing campaign requires a single 25kg trial bag or a full 10-ton bulk container drop, your freight leaves our loading dock within 48 hours.
2. Advanced Eco-Friendly Catalytic Refinement
Our technical division utilizes an advanced, single-step catalytic hydrogenation of nitrobenzene over noble metal catalyst beds rather than messy, traditional iron-acid reduction paths. This technical advantage ensures an ultra-clean reaction output, locking moisture levels down to a strict maximum of 0.50% and keeping melting ranges tightly bound between 186°C and 188°C.
We monitor every fractionating loop via gas chromatography (GC) to guarantee exact isomer consistency across multi-year purchase contracts. Your quality assurance team receives an official, factory-direct Certificate of Analysis (COA) before the cargo arrives at your plant door.
4-Aminophenol's Procurement Guide
Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)
2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ：1kg
3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services
FAQ
It comes down to impurity control inside your acetylation reactors. Lower-grade chemical lots often contain residual iron fines, high water weight, and structural isomers that skew reaction kinetics and trigger unwanted side-coupling. Our ≥98.0% pure 4-Aminophenol ensures clean, rapid acetylation with acetic anhydride, optimizing your final paracetamol isolation yield and cutting down your overall downstream purification costs.
This bifunctional aromatic amine is highly vulnerable to moisture uptake, atmospheric oxygen, and direct UV light exposure. Contact with air causes the white crystals to oxidize into a dead, dark brown aggregate that compromises its reduction power in hair dye and photographic developer formulations. To safeguard the complete shelf life, warehouse personnel must store the material inside hermetically sealed containers in a cool, dry, and pitch-dark chemical facility completely isolated from aggressive acids and strong oxidizers.
The compound carries serious regulatory handling flags, with an oral LD₅₀ of 375 mg/kg documented in rabbit models. It is officially classified as harmful if swallowed, an active skin sensitizer, and highly toxic to local aquatic ecosystems. Material handlers must utilize appropriate personal protective equipment (PPE)—including heavy-duty nitrile gloves, chemical splash goggles, and face shields—and always discharge the raw powder inside a negative-pressure fume hood or a sharply ventilated processing zone.
We support diverse procurement tracks depending on your project phase: our standard MOQ starts at 25kg (one standard woven bag) to accommodate initial laboratory screening and pilot-scale formulation trials. For warehouse spot items, we ship out within 1 to 2 business days. Large commercial contracts and tonnage freight orders (10 MT and above) clear our logistics grid and customs documentation loops within 5 to 7 business days.
Related References
Manufacturer of 4-Aminophenol
Achievements
Advantage
Service
FAQ
Advice on Shipping
Achievements
Zhishang Bio is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang Bio will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 4-Aminophenol manufacturer, Zhi shang Bio has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Advantage
Zhishang Bio is a professional enterprise engaged in the research and development, production, and sales of chemical raw materials. It has a strong supply chain system and strict quality control standards to ensure the provision of high-quality products with high purity and stability to customers.
Zhishang Bio’s core strength is its independent research and design capabilities. It has advanced production equipment, testing laboratories and can customize chemical raw materials to meet the market demands. This includes pharmaceuticals, electronic, coatings and agricultural applications.
Zhishang Bio’s supply chain management is based on long-term relationships with domestic and international suppliers of high quality to guarantee a stable supply, optimize logistic systems, and achieve efficient distribution. This helps reduce the cost of customer purchases.
We adhere to international environmental standards and we also adhere to the concept that environmental protection and safety production are important. All production processes must comply with these standards in order to guarantee that our products will be green and sustainable.
With a professional technical team and comprehensive after-sales service, Zhishang Bio can provide customers with precise technical support, solve application problems, and help customers enhance product competitiveness.
We are always customer-oriented and committed to becoming a trusted chemical raw material partner.
Service
Zhishang Biography is dedicated to using clients extensive and expert service, including chemical raw material. The customers will certainly receive hassle-free, efficient and one-stop options.
1. Custom-made Supply Solutions
Zhishang Bio provides tailored services for clients in the chemical basic material sector, including special bit dimension, solvent residue control, stability optimizations and more. Clients can personalize their services to satisfy details requirements in industries such as drugs, electronic devices, and finishings.
2. Strict quality assurance
Zhishang Bio utilizes advanced screening equipment and stringent quality examination procedures, in addition to various other files, to guarantee that every batch of products is certified with international criteria such ISO GMP, REACH, and so on. Customers are also given with full quality records and conformity documents.
The supply chain is secure
Zhishang Bio has actually established lasting calculated collaborations with worldwide makers of top notch raw materials to make certain a secure supply, maximize the storage facility and logistics system, and assistance both small-scale examinations and large orders. It adjusted to the changing requirements of clients by responding flexibly to these changes.
4. Technical support
Zhishang Bio’s technical group can offer suggestions on product applications, formula optimization and analysis of industry patterns to aid clients fix technological troubles during production and boost item efficiency.
5. Efficient after-sales service
Zhishang Bio provides complete monitoring, reacts to client requests and delivers promptly. This will certainly make certain customer complete satisfaction.
Zhishang Biography intends to help consumers expand their service by providing the very best solutions and chemical resources.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.
