6-Iodoquinazolin-4-one CAS 16064-08-7
6-Iodoquinazolin-4-one CAS 16064-08-7
- Surfactant Appearance: powder
- Proportion: Minimum 99.0%
- Inventory: In stock
- Sample: In stock
- Zhishang Chemical: Supplier and manufacturer of 6-Iodoquinazolin-4-one
Basic Info of 6-Iodoquinazolin-4-one
| Item | Specification |
|---|---|
| Product Name | 6-Iodoquinazolin-4-one |
| CAS Number | 16064-08-7 |
| Molecular Formula | C8H5IN2O |
| Molecular Weight | 272.04 |
| Appearance | Off-white to light yellow powder |
| Application | Pharmaceutical Intermediate, Organic Synthesis, Research Chemical |
What is 6-Iodoquinazolin-4-one？
6-Iodoquinazolin-4-one is a halogen-substituted quinazoline derivative commonly employed as an intermediate in organic synthesis and pharmaceutical research. It is a useful building-block for the preparation biologically active compounds and kinase inhibition candidates. This compound is often used in the development of synthetic routes, medicinal chemistry, lead optimization, and other studies involving molecules based on quinazoline.
Benefits of Technical Advantage High-Molecular Stability for Research Applications 6-Iodoquinazolin-4-one features a molecular weight of 272.04 g/mol and a stable quinazolinone scaffold, making it a reliable building block for medicinal chemistry and heterocyclic synthesis projects.
Product Packaging
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Cross-Coupling reactions are possible with this reaction
Researchers can quickly construct quinazoline derivatives with the iodine functionality, which provides an efficient reaction site for palladium catalyzed reactions. This is useful for lead optimization studies and SAR.
High-purity Materials for Synthetic Development
The research-grade material supplied is typically >=98% pure, allowing for reproducible reactions and reducing the purification required during downstream synthesis.
Thermodynamic Characteristics
The compound has a melting temperature of 272-274degC, and a density of around 2.1g/cm3. It exhibits good thermal stability when handled and stored in laboratory environments.
FAQ
6-Iodoquinazolin-4-one is primarily used as a synthetic intermediate in medicinal chemistry, pharmaceutical research, and heterocyclic compound development. It is often incorporated into the synthesis of quinazoline-based molecules for biological evaluation.
The compound contains both a quinazolinone core and an iodine substituent, making it a valuable precursor for structural modification and lead optimization in drug discovery programs.
Yes. The iodine group can serve as a reactive site in various palladium-catalyzed coupling reactions, enabling the synthesis of more complex quinazoline derivatives.
The product should be stored in a tightly sealed container under cool, dry conditions and protected from direct light and moisture to maintain stability.
When selecting a supplier, it is recommended to evaluate product quality standards, documentation availability, manufacturing capability, and supply reliability to ensure consistent procurement.
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