PRODUCT
Zhishang Bio 6-paradol CAS 27113-22-0
CAS:27113-22-0 | C17H26O3 |MW：278.39 | EINECS NO：248-228-1
Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Transporta: Ocean, Land,Air, DHL，TNT
Port: Shanghai Port, Qingdao Port
Product Images & Packaging
Describe
6-Paradol (CAS 27113-22-0), also known as gingerol in Chinese, is a naturally occurring phenolic ketone compound. It mainly comes from the roots and stems of the ginger plant in the Zingiberaceae family, as well as the seeds of Guinea pepper. Its chemical name is 1-(4-hydroxy-3-methoxyphenyl)-decane-3-ketone, with the molecular formula of C₁₇H₂₆O₃ and a molecular weight of 278.39.
In terms of structure, 6-Paradol is closely related to 6-shogaol and is considered to be one of the main metabolites of 6-gingerol in the body.
As a highly pure natural product, 6-Paradol powder has attracted much attention in the research field. It does not belong to the common gingerol family, but its pharmacological activity is also extensive. Studies have shown that 6-Paradol exhibits significant anti-hyperglycemic activity and anti-obesity potential in metabolic research. For example, in animal experiments, it can lower blood sugar levels and inhibit weight gain. As a professional supplier and manufacturer of 6-Paradol, we provide 6-Paradol research chemicals with a purity of over 98%, suitable for mechanism exploration at the cellular and molecular levels.
| 6-paradol Basic information |
| Product Name: | 6-paradol |
| Synonyms: | 1-(4-hydroxy-3-methoxyphenyl)decan-5-one;3-Decanone, 1-(4-hydroxy-3-methoxyphenyl)-;6-paradol;PARADOL;1-(3-Methoxy-4-hydroxyphenyl)-3-decanone;1-(4-Hydroxy-3-methoxyphenyl)decan-3-one;1-(4-Hydroxy-3-methoxyphenyl)-3-decanone;5-Paradol |
| CAS: | 27113-22-0 |
| MF: | C17H26O3 |
| MW: | 278.39 |
| EINECS: | 248-228-1 |
| Product Categories: | |
| Mol File: | 27113-22-0.mol |
| 6-paradol Chemical Properties |
| Boiling point | 406.4±30.0 °C(Predicted) |
| density | 1.0690 g/cm3 |
| refractive index | 1.5232 (589.3 nm 20℃) |
| FEMA | 4665 | 1-(4-HYDROXY-3-METHOXYPHENYL)DECAN-3-ONE |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 10.02±0.20(Predicted) |
| color | White to Brown |
| Odor | spicy herbal |
| Odor Type | spicy |
| JECFA Number | 2021 |
6-Paradol Bulk Supply
As a high-purity natural product for scientific research, 6-Paradol powder, due to its diverse biological activities and clear mechanism of action, has become a hot research tool molecule in the fields of metabolic diseases, neuroprotection and anti-tumor research.
Anti-inflammatory activity and antioxidant properties – Ideal tool for neuroprotection research: 6-Paradol exhibits clear anti-inflammatory and antioxidant properties.
In vitro experiments have shown that it can significantly inhibit the production of inflammatory factors such as nitric oxide (NO), IL-6, and TNF-α by mouse microglial cells (BV-2) induced by LPS. This effect is believed to be closely related to its ability to alleviate neuroinflammation and exert neuroprotective effects after cerebral ischemia. Therefore, for researchers studying central nervous system diseases such as multiple sclerosis and Alzheimer’s disease, 6-Paradol is an ideal candidate molecule for exploring the anti-inflammatory-neuroprotection pathway.
Metabolic Activity – Potent Molecules for Anti-obesity and Hypoglycemic Research: 6-Paradol exhibits particularly significant value in metabolic studies. It can promote glucose utilization in a concentration-dependent manner in 3T3-L1 adipocytes and C2C12 myotube cells. In a mouse model of obesity induced by a high-fat diet, it significantly reduced blood glucose, cholesterol, and body weight at an oral dose of 6.75 mg/kg/day. This series of in vitro and in vivo data supports the potential of 6-Paradol as a lead molecule for developing anti-obesity and anti-hyperglycemic functional foods or drugs.
Antitumor activity and pharmacokinetic studies: The research indicates that 6-Paradol has the ability to inhibit the proliferation and induce apoptosis in various tumor cells. For instance, in colon cancer HCT116 cells, it can down-regulate the expression of the STAT3 signaling pathway and hexokinase 2, and inhibit the glycolytic level and clonogenic ability. Moreover, studies on its metabolic fate have identified 32 in vivo metabolites, providing crucial data support for a deeper understanding of its bioavailability and mechanism of action.
As a professional supplier of 6-Paradol, we offer high-purity (≥98%) 6-Paradol powder. We support scientific research procurement ranging from milligram to gram levels, and can provide comprehensive quality inspection reports (COA) to ensure consistency across batches.
Related References
Manufacturer of 6-paradol
Achievements
Advantage
Service
FAQ
Advice on Shipping
Achievements
Zhishang Bio is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang Bio will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 6-paradol manufacturer, Zhi shang Bio has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Advantage
Zhishang Bio is a professional enterprise engaged in the research and development, production, and sales of chemical raw materials. It has a strong supply chain system and strict quality control standards to ensure the provision of high-quality products with high purity and stability to customers.
Zhishang Bio’s core strength is its independent research and design capabilities. It has advanced production equipment, testing laboratories and can customize chemical raw materials to meet the market demands. This includes pharmaceuticals, electronic, coatings and agricultural applications.
Zhishang Bio’s supply chain management is based on long-term relationships with domestic and international suppliers of high quality to guarantee a stable supply, optimize logistic systems, and achieve efficient distribution. This helps reduce the cost of customer purchases.
We adhere to international environmental standards and we also adhere to the concept that environmental protection and safety production are important. All production processes must comply with these standards in order to guarantee that our products will be green and sustainable.
With a professional technical team and comprehensive after-sales service, Zhishang Bio can provide customers with precise technical support, solve application problems, and help customers enhance product competitiveness.
We are always customer-oriented and committed to becoming a trusted chemical raw material partner.
Service
Zhishang Biography is dedicated to using clients extensive and expert service, including chemical raw material. The customers will certainly receive hassle-free, efficient and one-stop options.
1. Custom-made Supply Solutions
Zhishang Bio provides tailored services for clients in the chemical basic material sector, including special bit dimension, solvent residue control, stability optimizations and more. Clients can personalize their services to satisfy details requirements in industries such as drugs, electronic devices, and finishings.
2. Strict quality assurance
Zhishang Bio utilizes advanced screening equipment and stringent quality examination procedures, in addition to various other files, to guarantee that every batch of products is certified with international criteria such ISO GMP, REACH, and so on. Customers are also given with full quality records and conformity documents.
The supply chain is secure
Zhishang Bio has actually established lasting calculated collaborations with worldwide makers of top notch raw materials to make certain a secure supply, maximize the storage facility and logistics system, and assistance both small-scale examinations and large orders. It adjusted to the changing requirements of clients by responding flexibly to these changes.
4. Technical support
Zhishang Bio’s technical group can offer suggestions on product applications, formula optimization and analysis of industry patterns to aid clients fix technological troubles during production and boost item efficiency.
5. Efficient after-sales service
Zhishang Bio provides complete monitoring, reacts to client requests and delivers promptly. This will certainly make certain customer complete satisfaction.
Zhishang Biography intends to help consumers expand their service by providing the very best solutions and chemical resources.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.
