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Azithromycin

Zhishang Bio Azithromycin CAS 83905-01-5

CAS:83905-01-5 | C38H72N2O12 |MW:748.98 | EINECS NO:617-500-5

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Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP

Transporta: Ocean, Land,Air, DHL,TNT

Port: Shanghai Port, Qingdao Port

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Azithromycin
Azithromycin
Azithromycin

Describe

Azithromycin, a commonly used antibiotic, is widely used in clinical practice. It has many advantages, including a wide spectrum of antibacterial action, minimal irritation of the gastrointestinal tract and rapid oral absorption. Both adults and children can use it.

Azithromycin has fewer side effects than cephalosporins and is therefore the most common antibiotic used in Chinese hospitals to treat bacterial infections.

Azithromycin, a semi-synthetic derivative of macrolides in the second generation, is structurally distinct from erythromycin. It inserts a substituted methyl nitrogen at the 9a positions of the erythromycin ring. This results in a macrolide with 15 members.

Azithromycin has a similar mechanism of action to erythromycin. It binds to the 50S subunit in sensitive bacterial ribosomes and inhibits RNA-dependent protein synthesis, while exerting its antibacterial properties.

Azithromycin is as effective against Chlamydia as erythromycin. Azithromycin is significantly more effective than erythromycin against gram negative bacteria. Its antibacterial action against influenza bacilli, Neisseria gonorrhoeae, and Neisseria meningitidis are also four times as strong.

Azithromycin is about two times more effective against Legionella, and has a significantly higher antibacterial effect against Enterobacteriaceae. The MIC of the vast majority Gram-negative bacteria is below 1 mg/l.

Staphylococcus Aureus and Streptococcus Pyogenes are cross resistant to Azithromycin. It is also effective against Toxoplasma pallidum and Toxoplasma gondii.

Azithromycin can be used to treat infections of the respiratory tract, urinary tract, reproductive tract, soft tissues, and skin caused by sensitive bacteria.

Product Name:Azithromycin
Synonyms:10% aqueous azithromycin;
CAS:83905-01-5
MF:C38H72N2O12
MW:748.98
EINECS:617-500-5
Product Categories:API;Pharmaceutical intermediate;
Mol File:83905-01-5.mol
 
Azithromycin Chemical Properties
Melting point 113-115°C
alpha D20 -37° (c = 1 in CHCl3)
Boiling point 822.1±65.0 °C(Predicted)
density 1.18±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Practically insoluble in water, freely soluble in anhydrous ethanol and in methylene chloride.
pkapKa 8.74 (H2O t=25 I=0.167) (Uncertain);9.45(H2O t=25 I=0.167) (Uncertain)
form Solid
color White to Off-White

Application

Azithromycin Application Certificate

Azithromycin can be used to treat acute pharyngitis and acute tonsillitis due to pyogenic Streptococcus. It is also prescribed for sinusitis as well as acute otitis, acute bronchitis and acute exacerbation chronic bronchitis.

Azithromycin can be used to treat pneumonia caused by Streptococcus pneumoniae, influenza bacteria, or Mycoplasma pneumoniae.

Azithromycin can be used to treat urethritis and cervicitis caused by Chlamydia, non-multidrug resistant Neisseria gonorrhoeae and simple genital infection caused by Neisseria.

Azithromycin can be used to treat skin and soft tissues infections caused by sensitive bacteria.

Azithromycin is more effective against Gram-positive bacteria as well as Gram-negative bacteria like Haemophilus flue, Salmonella and Escherichia Coli.

Azithromycin has a good tolerance and is acid-stable. It is effective against respiratory tract infections as well as skin and soft tissues infections, sexually-transmitted diseases, etc. This is due to sensitive bacterial strains.

Azithromycin can be used to treat a variety of infections caused by sensitive bacteria. This includes respiratory infections, skin infections, and soft tissue infections.

Azithromycin can be used to treat respiratory tract infections (RTI), urinary tract infection, skin and soft tissues infections, and sexually-transmitted diseases.

Related References

Manufacturer of Azithromycin

Company Info

Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
 
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.

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