Bempedoic acid CAS 738606-46-7 supplier | Zhishangbio
Bempedoic acid CAS 738606-46-7
- Surfactant Appearance: powder
- Proportion: Minimum 99.0%
- Inventory: In stock
- Sample: In stock
- Zhishang Chemical: Supplier and manufacturer of Bempedoic acid
Basic Info of Bempedoic acid
| Bempedoic acid Chemical Properties |
| Melting point | 87 – 92°C |
| Boiling point | 506.5±35.0 °C(Predicted) |
| density | 1.045±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 4.55±0.45(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C19H36O5/c1-18(2,16(21)22)13-9-5-7-11-15(20)12-8-6-10-14-19(3,4)17(23)24/h15,20H,5-14H2,1-4H3,(H,21,22)(H,23,24) |
| InChIKey | HYHMLYSLQUKXKP-UHFFFAOYSA-N |
What is Bempedoic acid?
What is Bempedoic acid?
Bempedoic acid, with CAS number 738606-46-7, has the molecular formula C ₁₉ H ₃₆ O ₅ and a molecular weight of 344.49. It is a first-in-class ATP-citrate lyase prevention created by Esperion Therapeutics. It was accepted by the FDA in February 2020 and is marketed under the name Nexletol. It is usually integrated with ezetimibe in a substance formulation called Nexlizet for enhanced lipid-lowering therapy.
From a chemical structure point of view, it is 8-hydroxy-2,2,14,14- tetramethylpentadecanoic acid. It appears as a white strong and is soluble in DMSO (> 25 mg/mL). The routine purity can reach over 98%. Its device of action is quite unique: as a prodrug, it needs to be turned on by long-chain fatty acyl-CoA synthetase 1 in the liver before it ends up being an energetic ACL inhibitor. Considering that this triggering enzyme is barely revealed in skeletal muscular tissues, the impact of Bempedoic acid is “locked” in the liver, avoiding muscle-related adverse effects at the source.
Scientifically, it is mostly utilized for heterozygous familial hypercholesterolemia and atherosclerotic heart diseases people who are intolerant to statins or whose LDL-C degrees still do not get to the target after statin therapy. It has been accepted by regulatory authorities in the USA, the European Union, and the UK, and so on.
Product Packaging
If you want to buy Bempedoic acid, pls contact us to get a free quote.
Superior Bempedoic acid Series | Reliable Quality & Sufficient Supply
As an expert provider of Bempedoic acid, we have a deep understanding of this high-purity lipid-lowering substance from resources to shipment based upon lasting participation with the source factory.
Source control, set consistency. The research-grade Bempedoic acid has incredibly high demands for purity and batch-to-batch stability – even a slight distinction in the energetic component can affect the results of cell experiments. Our provided products can reach over 98% purity, and each set comes with a COA report, with set retention examples traceable to make certain that each batch of goods you get is consistent with the example.
Adaptable supply, flexible delivery. Research study clients can put orders beginning with 5mg and 10mg, which can be made use of for in vitro task screening or cell experiments; mass acquisitions can be supplied in 100mg, 500mg, and even gram-level amounts, satisfying the whole process demands from in vivo effectiveness verification to formula research. Routine orders are sent off from the East China storage facility, and the goods will show up within 5-7 working days.
Professional assistance, threat avoidance. Bempedoic acid has excellent solubility in DMSO (> 40 mg/mL), but it is insoluble in water and ethanol. Our technical group can give solvent choice and solution pointers based upon your speculative situations.
FAQ
We are a comprehensive supplier integrating industry and trade (zhishangbio), deeply bound with compliant source factories, equivalent to a first-hand source of goods. Research clients and small-scale R&D units can save on the premium of intermediate links when they come to us.
Soluble in DMSO (40 mg/mL), insoluble in water and ethanol. It is recommended to prepare the storage solution with DMSO, dilute it with culture medium or PBS to the working concentration, and prepare it for immediate use to avoid repeated freezing and thawing.
Research clients support a minimum order of 5mg for preliminary activity screening. Standard specifications include 5mg, 10mg, 25mg, 50mg, 100mg, etc. Spot orders will be shipped within 1-2 working days.
Each batch of products comes with a complete COA report (including key indicators such as HPLC purity and moisture), and the batch samples can be traced. Bulk procurement can agree to retain samples for comparison, and batches with deviations beyond the range can be negotiated for handling.
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Bempedoic acid Supplier and Manufacturer
As a Bempedoic acid supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best Bempedoic acid raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for Bempedoic acid and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Hot Products
