Zhishang Bio Technology|Supplier of pharmaceutical intermediates, pesticide intermediates and cosmetics raw materials

PRODUCT

Benzbromarone

Zhishang Bio Benzbromarone CAS 3562-84-3

CAS:3562-84-3  | C17H12Br2O3 |MW:424.08 | EINECS NO:222-630-7

Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union

Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP

Transporta: Ocean, Land,Air, DHL,TNT

Port: Shanghai Port, Qingdao Port

Product Images & Packaging

Benzbromarone
Benzbromarone
Benzbromarone

Benzbromarone's parameters

Benzbromarone Chemical Properties
Melting point 151°
Boiling point 514.1±50.0 °C(Predicted)
density 1.6211 (rough estimate)
refractive index 1.6010 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility Practically insoluble in water, freely soluble in acetone and in methylene chloride, sparingly soluble in ethanol (96 per cent).
pka4.66±0.25(Predicted)
form Solid
color White to Light yellow
Merck 14,1065

benzbromarone vs allopurinol

ParameterBenzbromaroneAllopurinol
MechanismURAT1 inhibitor (promotes uric acid excretion)Xanthine oxidase inhibitor (reduces uric acid production)
IndicationUric acid underexcretion type hyperuricemiaUric acid overproduction type hyperuricemia
MetabolismPrimarily hepatic metabolismPrimarily renal excretion
Onset of ActionRapid (24-48 hours)Slow (2-3 weeks to reach steady state)
Hepatotoxicity RiskHigher (requires liver function monitoring)Lower
Nephrotoxicity RiskLow (caution in renal impairment)Higher (dose adjustment needed in renal impairment)
Drug InteractionsAntagonized by salicylatesSerious interactions with azathioprine/mercaptopurine
Suitable PatientsPatients with normal/mildly impaired renal functionPatients with renal impairment (with dose adjustment)
Common ADRsLiver dysfunction, GI disturbancesSkin rash, hypersensitivity, liver dysfunction
AdvantagesPotent uricosuric effect, ideal for underexcretorsPreferred for overproducers and renal impairment
ContraindicationsSevere hepatic/renal impairment, uric acid stonesHypersensitivity, pregnancy

 

The application of Benzbromarone

Benzbromarone API is a high-purity organic compound with the chemical name 3- (5-bromo-2-benzofuranyl) -2-ethyl-1-benzofuran-7-carboxylic acid.

The powder is white to off-white with distinct crystalline properties. Benzbromarone has a molecular mass of 424.09 g/mol and a melting temperature of 150-153. It is stable at room temperature, both physically and chemically.

Water-soluble, but easily soluble with organic solvents like ethanol and Acetone

benzbromarone uses

1. Gout can be treated with Benzbromarone combined with traditional Chinese medicine. Combining traditional Chinese medicine with traditional Chinese medicines has proven to be very effective in treating gout, gastrointestinal diseases and other related conditions.

Benzbromarone promotes uric-acid excretion, protecting kidney function. By reducing blood uric-acid concentration, proteinuria and deposition of uric acids in the interstitium are reduced.

3. Benzbromarone is combined with specific electromagnetic wave to treat gouty arthritis. The specific electromagnetic spectrum of specific electromagnetic waves has a thermal effect that can improve blood circulation in the affected area and the pH value, which inhibits the formation of urate crystalline crystals. It also plays an analgesic and anti-inflammatory role.

Benzbromarone’s Procurement Guide

Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)

2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ:1kg

3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services

Paeonol

FAQ

Yes, we have our own factory called ” ZhiShang Industry Group “

Yes, we have GMP certificate for some products, and we can provide DMF as well.

 -Quality you require, eg. Assay, Purity, or single impurity

-Quantity you need

-Standard you want, such as USP, EP, JP etc.

Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well.

For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment. 

For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 day.

Related References

Manufacturer of Benzbromarone

Company Info

Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
 
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.

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