PRODUCT
D-Glucurone CAS 32449-92-6
CAS:32449-92-6 | C6H8O6 |MW：176.12 | EINECS NO：251-053-3
Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Transporta: Ocean, Land,Air, DHL，TNT
Port: Shanghai Port, Qingdao Port
Description
D-glucuronide is used in clinical practice as a hepatoprotective agent, along with carnitine and biphenyl diastere. Its primary function is to increase the liver’s detoxification abilities and protect against liver toxins. It will decompose quickly in the body into glucuronic acids, which are essential for liver detoxification. It can bind to toxins, drugs and metabolites containing hydroxyl and amino groups, in the intestine or liver, creating non-toxic “glucuronic acids conjugates” which are then excreted by the kidneys and the urine. This completes the detoxification process and protects the liver. It can also decrease the activity of the amylase enzyme in the liver. This prevents glycogen from easily being broken down and increases liver glycogen. In clinical practice it is used to treat food and drug poisoning, acute and chronic hepatitis as well as early cirrhosis. It is an important component in human connective tissues and collagen. Therefore, it can also be used to treat diseases caused by collagen such as arthritis. Drug-induced liver diseases are liver damages caused by drugs and their metabolites. It doesn’t matter if you have a liver disease history, as long as the liver problem occurs after taking a drug, then it is a liver disorder. The detoxification process is very straightforward: After oral absorption, glucuronic acids are formed, which bind with toxins either in the liver or in the intestines and are then excreted as a non-toxic substance. It is commonly used to treat food and drug poisoning, as well as diseases like hepatitis and cirrhosis. It is used to make tissue components such as cartilage and periosteum. D-glucuronide: Chemical Knowledge When exposed to light, it becomes a white powder or crystalline granule with little smell, a bitter taste, and a color that gradually darkens. After dissolving the lactones in water, they will convert into glucuronic acids, creating an equilibrium and causing the solution to become acidic. It dissolves readily in water and methanol but only slightly in ethanol. The melting point of the compound is 170-176 degrees Fahrenheit, while its specific rotation is 18.0 degrees to 20.0 degree Fahrenheit (0.1g/ml). After entering the body under the action enzymes, the lactone ring opens and becomes glucuronic to exert its effects. Glucuronic Acid is a detoxifying substance that plays a vital role in the body. It can bind to drugs and toxins that contain carboxyls to form low-toxicity or non-toxic complexes. It also helps to detoxify and protects the liver. D-glucuronide is commonly found in white tablets.
Product Images & Packaging
Product Parameters
| D-Glucurone Chemical Properties |
| Melting point | 172-175 °C (lit.) |
| alpha | 19 º (c=10, H2O) |
| Boiling point | 227.71°C (rough estimate) |
| density | 1,76 g/cm3 |
| refractive index | 18.5 ° (C=5, H2O) |
| storage temp. | Store below +30°C. |
| solubility | water: soluble25mg/mL, clear, colorless |
| pka | 11.96±0.60(Predicted) |
| form | Crystals or Crystalline Powder |
| color | White |
| Odor | at 100.00 %. very mild mentholic |
| Odor Type | mentholic |
| Optical Rotation | [α]24/D +18.8°, c = 8 in H2O |
| Water Solubility | SOLUBLE |
| Merck | 14,4467 |
| BRN | 83595 |
The application of D-Glucurone
1.D-Glucurone’s primary use is to detoxify and protect the liver, thereby safeguarding its health. The liver is a vital detoxification organ.
The glucuronic acids produced by D-Glucurone decomposition can be combined with toxic chemicals, heavy metal ions and drug metabolites. The liver converts the glucuronic acid into non-toxic compounds that are excreted with urine. This reduces the burden of detoxification on the liver, and protects liver cells.
It is used in clinical treatment as an adjuvant for acute and chronic Hepatitis. This includes viral hepatitis or steatohepatitis. It can improve liver detoxification, reduce the inflammatory response of liver cells, and help to gradually restore normal liver metabolism.
D-Glucurone is effective in treating patients with early cirrhosis. It can reduce the accumulation of liver fat, increase glycogen synthesis in the liver, slow down cirrhosis progression, and improve liver function.
It is also used as an antidote to poisoning from food or drugs. This includes accidental ingestion of toxic plants and animals, drug overdoses, etc. D-Glucurone, when used promptly, can help to reduce liver damage and toxins.
2. D-Glucurone can be used to treat diseases related to D-Glucurone and maintain body functions.
D-Glucurone, a component of connective tissues and collagen, is found in cartilage, periosteum and the capsules of joints and nerves. D-Glucurone supplementation can be used to provide raw materials that are needed for tissue repair and maintenance. It is used to treat arthritis and rheumatic disease, reducing joint inflammation and improving joint function.
D-Glucurone has a similar adjuvant effect in treating jaundice. Jaundice can be caused by an abnormal liver metabolism or obstruction of bilirubin expulsion. It can help improve liver metabolism, promote the conversion of bilirubin and aid in its excretion, and alleviate skin and sclera symptoms, particularly for patients with hepatitis complex with jaundice.
3. Health maintenance daily application
D-Glucurone has many applications for daily health maintenance. D-Glucurone, a liver protector and auxiliary ingredient in many products that are regularly used to maintain liver health, is now added to regular health products. It’s suitable for those with a heavy liver burden, such as people who stay up late or drink alcohol and eat irregularly.
It can be used to protect the health of certain populations. For example, practitioners exposed to toxic chemicals and heavy metals for long periods, or patients taking drugs which may cause liver damage for long periods. Under the supervision of a physician, taking D-Glucurone can reduce the risk for liver damage.
D-Glucurone 's Procurement Guide
Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)
2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ：1kg
3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services
FAQ
Yes, we have our own factory called ” ZhiShang Industry Group “
Yes, we have GMP certificate for some products, and we can provide DMF as well.
-Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well.
For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 day.
Related References
Manufacturer of D-Glucurone
Achievements
Advantage
Service
FAQ
Advice on Shipping
Achievements
Zhishang Bio is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang Bio will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional D-Glucurone manufacturer, Zhi shang Bio has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Advantage
Zhishang Bio is a professional enterprise engaged in the research and development, production, and sales of chemical raw materials. It has a strong supply chain system and strict quality control standards to ensure the provision of high-quality products with high purity and stability to customers.
Zhishang Bio’s core strength is its independent research and design capabilities. It has advanced production equipment, testing laboratories and can customize chemical raw materials to meet the market demands. This includes pharmaceuticals, electronic, coatings and agricultural applications.
Zhishang Bio’s supply chain management is based on long-term relationships with domestic and international suppliers of high quality to guarantee a stable supply, optimize logistic systems, and achieve efficient distribution. This helps reduce the cost of customer purchases.
We adhere to international environmental standards and we also adhere to the concept that environmental protection and safety production are important. All production processes must comply with these standards in order to guarantee that our products will be green and sustainable.
With a professional technical team and comprehensive after-sales service, Zhishang Bio can provide customers with precise technical support, solve application problems, and help customers enhance product competitiveness.
We are always customer-oriented and committed to becoming a trusted chemical raw material partner.
Service
Zhishang Biography is dedicated to using clients extensive and expert service, including chemical raw material. The customers will certainly receive hassle-free, efficient and one-stop options.
1. Custom-made Supply Solutions
Zhishang Bio provides tailored services for clients in the chemical basic material sector, including special bit dimension, solvent residue control, stability optimizations and more. Clients can personalize their services to satisfy details requirements in industries such as drugs, electronic devices, and finishings.
2. Strict quality assurance
Zhishang Bio utilizes advanced screening equipment and stringent quality examination procedures, in addition to various other files, to guarantee that every batch of products is certified with international criteria such ISO GMP, REACH, and so on. Customers are also given with full quality records and conformity documents.
The supply chain is secure
Zhishang Bio has actually established lasting calculated collaborations with worldwide makers of top notch raw materials to make certain a secure supply, maximize the storage facility and logistics system, and assistance both small-scale examinations and large orders. It adjusted to the changing requirements of clients by responding flexibly to these changes.
4. Technical support
Zhishang Bio’s technical group can offer suggestions on product applications, formula optimization and analysis of industry patterns to aid clients fix technological troubles during production and boost item efficiency.
5. Efficient after-sales service
Zhishang Bio provides complete monitoring, reacts to client requests and delivers promptly. This will certainly make certain customer complete satisfaction.
Zhishang Biography intends to help consumers expand their service by providing the very best solutions and chemical resources.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.
