Manufacturer Gossypol-acetic acid CAS 12542-36-8
Gossypol-acetic acid Description
Gossypol-acetic acid (CAS 12542-36-8), a highly refined polyphenolic binaphthalene complex carrying the molecular formula C₃₂H₃₄O₁₀, functions as a critical anti-tumor intermediate and reproductive biology reference standard across global medical research centers. Oncology engineers utilize this yellow crystalline matrix primarily for its role as a potent Bcl-2/Bcl-xl family antagonist, driving automated cell apoptosis screening inside deep-well testing plates. The raw material dissolves cleanly into solvents like acetone, DMSO, and ethanol within standard laboratory reaction flasks, yielding a uniform liquid vehicle for high-throughput screening. Because this specific acetate salt structure provides superior crystalline stability over raw gossypol, it functions as the benchmark molecule for advanced clinical cell signaling trails.
The Extraction and Stabilization Pathway
[Raw Cottonseed Oil Cake] ➔ [Multi-Stage Solvent Leaching] ➔ [Glacial Acetic Acid Complexation] ➔ [Low-Temp Recrystallization] ➔ [Gossypol-acetic acid ≥99%]
The workflow map above illustrates our specialized isolation sequence. This closed-loop refining path removes residual plant toxins and trace moisture, allowing us to enforce the following baseline specifications across every batch:
| Analytical Parameter | Checked Value Profile | Operational Benefit |
|---|---|---|
| Active Gossypol Acetate Assay | ≥ 99.00% (validated by HPLC) | Eliminates background assay drift |
| Free Glacial Acetic Acid | 10.00%–11.00% | Stabilizes the active crystal core |
| Loss on Drying Cap | ≤ 0.50% (Vacuum Oven) | Prevents premature material decay |
Gossypol-acetic acid Images & Packaging
Gossypol-acetic acid Parameters
| Gossypol-acetic acid Chemical Properties |
| Melting point | 164-168°C |
| storage temp. | −20°C |
| solubility | Soluble in acetone or methanol at 5mg/ml |
| form | Solid |
| color | Yellow to Very Dark Yellow |
| Major Application | food and beverages |
| InChIKey | NIOHNDKHQHVLKA-UHFFFAOYSA-N |
| SMILES | C12C(C(C)C)=C(C(O)=C(C=O)C=1C(O)=C(C1C(C)=CC3C(C(C)C)=C(O)C(O)=C(C=O)C=3C=1O)C(C)=C2)O.C(=O)(O)C |
| LogP | 6.157 (est) |
| CAS DataBase Reference | 12542-36-8(CAS DataBase Reference) |
| EPA Substance Registry System | Gossypol acetic acid (12542-36-8) |
Why Partner with Zhishang Bio?
1. Constant Kilo-Scale Buffers & Steady Plant Output
We shield your laboratory timelines from sudden raw material shortages by maintaining a constant 85-kilogram inventory buffer of standard amber vials at our specialized deep-freeze depots. Our manufacturing assets run continuous extraction and complexation loops that push out a steady monthly output of 150 kilograms of premium-grade powder. This large-scale infrastructure ensures you completely bypass market procurement bottlenecks and shipping delays. Whether your current academic trial requires a micro 1g vial or your commercial pilot manufacturing line requires a multi-kilogram industrial bulk drop, your cargo clears our transit dock within 24 hours.
2. Advanced Low-Temperature Glacial Complexation
Our technical division engineered a multi-stage fractional crystallization process using pure glacial acetic acid that forces purity levels up to a strict minimum of 99.00%. This advanced separation loop traps the volatile gossypol structure inside a highly stable crystal cage, stopping oxidation reactions inside your heating vats and lowering your downstream purification overheads. We monitor every fractionating lot via high-performance liquid chromatography (HPLC) to guarantee an exact optical isomer ratio across multi-year purchase contracts. Your quality assurance team receives an official, factory-direct Certificate of Analysis (COA) before the pressurized containers arrive at your facility.
Gossypol-acetic acid 's Procurement Guide
Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)
2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ：1kg
3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services
FAQ
It comes down to protecting the active aldehyde groups from rapid air oxidation. Unconjugated raw gossypol degrades quickly when exposed to ambient moisture and light, turning into a dead dark brown mass that skews your experimental baseline. By binding a single molecule of acetic acid to the gossypol core, our Gossypol-acetic acid creates a robust crystalline framework that safeguards the active molecule from air degradation, extending your shelf life significantly.
This polyphenolic substance is highly sensitive to ambient heat, atmospheric oxygen, and direct UV light exposure. Contact with warm air causes the acetic acid complex to dissociate, which destroys its analytical accuracy during cell signaling assays. To protect the complete 24-month shelf life, warehouse personnel must store the chemical inside tightly sealed amber glass containers under a dry nitrogen blanket held inside a continuous -20°C (-4°F) deep-freeze matrix.
Our analytical laboratory runs multi-stage HPLC checks paired with automated melting point apparatuses to chart the exact chemical profile of every lot. We map active purity, volatile loss on drying, trace metal profiles, and the exact ratio of bound acetic acid for every single batch before it leaves our dock. We archive identical retention samples from each batch to maintain an airtight, verifiable audit trail for your vendor qualification team.
We support diverse procurement tracks depending on your project phase: our standard MOQ starts at just 1g to accommodate initial laboratory screening and pilot-scale formulation trials. For warehouse spot items, we ship out within 1 to 2 business days under strict cold-chain tracking. Large commercial contracts and multi-kilogram freight orders clear our logistics grid, customs documentation loops, and export clearance certifications within 5 to 7 business days.
Related References
Pubchem-Gossypol-acetic acid
Manufacturer of Gossypol-acetic acid
Achievements
Advantage
Service
FAQ
Advice on Shipping
Achievements
Zhishang Bio is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang Bio will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional Gossypol-acetic acid manufacturer, Zhi shang Bio has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Advantage
Zhishang Bio is a professional enterprise engaged in the research and development, production, and sales of chemical raw materials. It has a strong supply chain system and strict quality control standards to ensure the provision of high-quality products with high purity and stability to customers.
Zhishang Bio’s core strength is its independent research and design capabilities. It has advanced production equipment, testing laboratories and can customize chemical raw materials to meet the market demands. This includes pharmaceuticals, electronic, coatings and agricultural applications.
Zhishang Bio’s supply chain management is based on long-term relationships with domestic and international suppliers of high quality to guarantee a stable supply, optimize logistic systems, and achieve efficient distribution. This helps reduce the cost of customer purchases.
We adhere to international environmental standards and we also adhere to the concept that environmental protection and safety production are important. All production processes must comply with these standards in order to guarantee that our products will be green and sustainable.
With a professional technical team and comprehensive after-sales service, Zhishang Bio can provide customers with precise technical support, solve application problems, and help customers enhance product competitiveness.
We are always customer-oriented and committed to becoming a trusted chemical raw material partner.
Service
Zhishang Biography is dedicated to using clients extensive and expert service, including chemical raw material. The customers will certainly receive hassle-free, efficient and one-stop options.
1. Custom-made Supply Solutions
Zhishang Bio provides tailored services for clients in the chemical basic material sector, including special bit dimension, solvent residue control, stability optimizations and more. Clients can personalize their services to satisfy details requirements in industries such as drugs, electronic devices, and finishings.
2. Strict quality assurance
Zhishang Bio utilizes advanced screening equipment and stringent quality examination procedures, in addition to various other files, to guarantee that every batch of products is certified with international criteria such ISO GMP, REACH, and so on. Customers are also given with full quality records and conformity documents.
The supply chain is secure
Zhishang Bio has actually established lasting calculated collaborations with worldwide makers of top notch raw materials to make certain a secure supply, maximize the storage facility and logistics system, and assistance both small-scale examinations and large orders. It adjusted to the changing requirements of clients by responding flexibly to these changes.
4. Technical support
Zhishang Bio’s technical group can offer suggestions on product applications, formula optimization and analysis of industry patterns to aid clients fix technological troubles during production and boost item efficiency.
5. Efficient after-sales service
Zhishang Bio provides complete monitoring, reacts to client requests and delivers promptly. This will certainly make certain customer complete satisfaction.
Zhishang Biography intends to help consumers expand their service by providing the very best solutions and chemical resources.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.
