Zhishang Bio Technology|Supplier of pharmaceutical intermediates, pesticide intermediates and cosmetics raw materials

PRODUCT

Hydroxyacetone

Hydroxyacetone (Acetol) 97% | CAS 116-09-6 | Pharma Grade

Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union

Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP

Transporta: Ocean, Land,Air, DHL,TNT

Port: Shanghai Port, Qingdao Port

Description

One thing experienced process chemists know: the same solvent from different suppliers can behave differently in a critical application. This isn’t usually a purity issue at the headline level — it’s trace impurities from different manufacturing routes that affect sensitive reactions or separations. When it matters, sourcing from a consistent producer matters.

For buyers comparing Hydroxyacetone across multiple suppliers: compare the COA format, not just the numbers. A supplier whose COA includes method references, batch-specific data (not specification ranges), and contact information for technical queries is providing better quality assurance than one who provides the minimum. The COA format reflects the quality culture.

Product Images & Packaging

Hydroxyacetone
Hydroxyacetone
Hydroxyacetone

Product Parameters

Hydroxyacetone Chemical Properties
Melting point -17 °C (lit.)
Boiling point 145-146 °C (lit.)
density 1.082 g/mL at 25 °C (lit.)
vapor pressure 9.01hPa at 25℃
refractive index n20/D 1.425(lit.)
FEMA 4462 | HYDROXYACETONE
Fp 133 °F
storage temp. 2-8°C
solubility water: miscible
pka13.14±0.10(Predicted)
form clear liquid
color Colorless liquid
Specific Gravity1.090 (20/4℃)

The application of Hydroxyacetone

Different industry sectors use Hydroxyacetone for different reasons. The common thread is that the chemistry works — but what ‘works’ means varies considerably by context.

  1. Pharmaceutical process solvent use

Hydroxyacetone is used as a reaction solvent or recrystallization medium in pharmaceutical synthesis. Residual solvent control per ICH Q3C applies; the compound’s classification determines permitted daily exposure limits.

  1. Coating and paint applications

Coating formulations use Hydroxyacetone as a cosolvent, flow modifier, or carrier medium to achieve target viscosity, open time, and film formation characteristics. Its evaporation rate relative to film formation and compatibility with resins are key selection factors.

  1. Extraction and separation applications

Liquid-liquid and solid-phase extraction processes in analytical chemistry and industrial purification may use Hydroxyacetone. Partition coefficients, mutual solubility, and phase separation behavior guide solvent selection.

  1. Adhesive and sealant formulations

Adhesive and sealant formulations use solvents including Hydroxyacetone to control viscosity and workability during application. The solvent’s evaporation characteristics after application affect open time and bond formation.

  1. Industrial cleaning and degreasing

Industrial cleaning and degreasing use Hydroxyacetone where its solvency power for oils and contaminants, combined with its physical and environmental profile, makes it appropriate. Flash point and volatility affect handling requirements.

Hydroxyacetone's Procurement Guide

Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)

2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ:1kg

3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services

Paeonol

FAQ

Three grades are suitable for most applications. The industrial grade is suitable for manufacturing applications that don’t require regulatory documentation other than a standard COA. Purity typically exceeds 98.0%. Most buyers choose pure grade (>=99.5%), which has tighter impurity controls and documented test results in the COA. The pharmaceutical grade comes with a full documentation package, including heavy metals below 20 ppm and residual solvents as per ICH Q3C. We can determine the grade based on your end-use application.

The most important factor is grade. A pharmaceutical-grade product is significantly more expensive than an industrial one due to the cost of testing. Order volume is important after that — 200 kg in one order or more gets you a better price per unit than 1kg samples. Prices can fluctuate due to raw material availability, particularly for products that have limited supply upstream. Packaging is also important: IBC totes can reduce packaging costs per kg at large volumes. To receive an accurate quote, please specify the grade, quantity, packing, and destination. Quotes are based on the actual requirements and not catalog prices.

For most incoming QC protocol, a 1 kg sample is sufficient. Check the COA to ensure that it shows the actual values measured, and not just “conforms” or “meets specs”. If your lab has the capability, run purity through Karl Fischer. Ask for the Karl Fischer results. Testing two batches prior to locking in volume is important for high-value applications. This ensures consistency of the batch, which is more important than a perfect sample. If your process calls for it, third-party pre-shipment testing (SGS or Bureau Veritas), is available to you at a cost.

If you keep the container in the correct conditions (sealed, cool, dry and away from light) it will last 36 months after its manufacture date. This is for original, unopened containers. Reseal the container immediately after opening and use it within a reasonable time frame. Heat and moisture are two of the main factors that accelerate degradation. This shelf life will shrink if you store in a hot warehouse in the summer. The SDS lists the incompatible conditions for storage and the materials that should be kept separate.

A few things are more important than the price. Are you dealing with a manufacturer, or a retailer? Manufacturers can control the process directly and investigate any quality problems. Prices may be lower, but traders have limited visibility of production. What kind of analytical equipment is on-site? HPLC, GC and Karl Fischer is the minimum requirement for a serious fine chemicals producer. Can they give COAs with actual results and not just pass/fail. Are they familiar with your country’s customs classification, documents, and freight arrangements? Asking for references from buyers of similar products is also a good idea.

Yes, as long as the process is within its limits. Purity specs that are tighter — for example, >=99.5% versus >=98.0% – can be achieved with more purification steps but at a higher price. It is generally not difficult to create custom packaging formats. Standard packages can include additional documentation, such as specific impurity limitations, custom SDS format, and DMF support. Please bring the technical requirements with you when you inquire, so that we can confirm feasibility before you commit.

Related References

Manufacturer of Hydroxyacetone

Company Info

Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
 
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.

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