Zhishang Bio Technology|Supplier of pharmaceutical intermediates, pesticide intermediates and cosmetics raw materials

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Hydroxypropyl methyl cellulose

Hydroxypropyl methyl cellulose CAS 9004-65-3

CAS:9004-65-3 | C3H7O* |MW:58.32 | EINECS NO:618-389-6

Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union

Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP

Transporta: Ocean, Land,Air, DHL,TNT

Port: Shanghai Port, Qingdao Port

Description

Hydroxypropyl methyl cellulose (HPMC) is a propylene glycol esters of methylcellulose in which the hydroxypropyl groups and the methyl groups have been bound by ether bonds to the anhydrous ring of glucose in cellulose. This results in a white or off-white cellulose powder, with the same characteristics of solubility in cold water and insolubility in hot water as methylcellulose. It is more soluble in organic solvents, such as chlorinated hydrocarbons, ethanol, anhydrous methanol, than it is in water. Hydroxypropyl methyl cellulose is soluble and has a surface activity in water. It forms a thin film after drying. After heating and cooling it, the sol is converted to gel. Cold drinks can use it alone or in combination, up to 1%. Hydroxypropyl methyl cellulose is widely used as a dispersant in many industries, including petrochemicals and papermaking. It can also be used as an excipient or capsule coating. Hydroxypropyl Methyl Cellulose: Chemical Properties Propylene glycol-ether of methylcellulose in which methyl and hydroxypropyl groups are bound through ether bonds to the anhydrous cellulose glucose ring. Different types of products have different proportions of hydroxypropyl and methoxy. Fibrous powders or granules that are white to grayish-white. Water and some organic solvents are soluble. The aqueous solution of Hydroxypropyl Methyl Cell is not soluble in ethanol. It forms a thin film after drying. After heating and cooling it, the gel transforms back to sol.

Product Images & Packaging

Hydroxypropyl methyl cellulose
Hydroxypropyl methyl cellulose
Hydroxypropyl methyl cellulose

Product Parameters

Hydroxypropyl methyl cellulose Chemical Properties
Melting point 225-230 °C
density 1.39
storage temp. room temp
solubility H2O: 50 mg/mL, clear to very faintly turbid, faintly yellow
form powder
color White to cream
OdorOdorless
PH5.0-8.0
biological sourceplant
Water Solubility SOLUBLE
Merck 14,4842

The application of Hydroxypropyl methyl cellulose

Hydroxypropyl methyl cellulose, Hydroxypropyl methyl cellulose, abbreviated as Hydroxypropyl methyl cellulose, is a non-ionic synthetic polymer made from natural polymer material cellulose through etherification modification.

Due to its unique chemical structure, which contains both hydrophilic hydroxypropoxy and hydroxymethyl groups, as well as hydrophobic methyl groups, Hydroxypropyl methyl cellulose exhibits excellent comprehensive properties such as water solubility, thickening, adhesion, film-forming, water retention, and surface activity.

More importantly, Hydroxypropyl methyl cellulose is non-toxic, odorless, safe for human health, and environmentally friendly, making it a green chemical. These characteristics span across numerous fields from traditional industry to high-tech biomaterials, becoming a true “industrial MSG” that plays an indispensable key role in countless products.

1、 Building materials industry: an indispensable core additive
In the field of construction, the application of Hydroxypropyl methyl cellulose is the most extensive and in-depth, and it is its largest consumer market. It is mainly used as an efficient water retaining agent, thickener, and retarder.

Dry mixed mortar: This is the core application scenario of Hydroxypropyl methyl cellulose. Adding Hydroxypropyl methyl cellulose can greatly improve the workability of mortar. Excellent water retention capacity can prevent moisture from being absorbed too quickly by the base layer or air, ensuring that cement has sufficient time to fully hydrate, thereby greatly improving the final bonding strength, compressive strength, and crack resistance of mortar, avoiding hollowing and cracking.

At the same time, the thickening effect of Hydroxypropyl methyl cellulose makes the mortar smoother, with better resistance to sagging, making it easier for construction personnel to scrape and operate, and improving construction efficiency. In machine sandblasting slurry, Hydroxypropyl methyl cellulose can also reduce pipeline resistance, making spraying smoother.

Gypsum based products: The solidification process of gypsum requires a stable moisture environment. The water retention effect of Hydroxypropyl methyl cellulose can effectively prevent gypsum from cracking, powdering, and other phenomena due to rapid water loss, while adjusting the setting time of gypsum to ensure the stability of product quality.

Cementitious self leveling mortar: In this type of product, Hydroxypropyl methyl cellulose not only provides appropriate viscosity and water retention, but also plays a more important role in preventing material delamination and segregation before solidification, ensuring the uniformity and stability of the material system, and thus obtaining a flat and sturdy ground.

2、 Pharmaceutical industry: safe and reliable pharmaceutical excipients
In the field of medicine, Hydroxypropyl methyl cellulose is widely used as an excipient in various drug formulations due to its non-toxic, non irritating, good biocompatibility, and non metabolic properties. Its main functions include:

Tablet coating: Hydroxypropyl methyl cellulose solution can form a tough and smooth thin film coating on the surface of the tablet core. This layer of film can mask the unpleasant odor of drugs, protect drugs from the effects of light and moisture, improve the appearance of tablets and make them easy to swallow, and work together with colored coating powder to achieve brand recognition.

The skeleton material of sustained-release formulations: This is a high-value application of Hydroxypropyl methyl cellulose. When used as the tablet skeleton, Hydroxypropyl methyl cell forms a layer of gel barrier when encountering water, and drugs must slowly diffuse and release through this layer of gel. By selecting different viscosity grades of Hydroxypropyl methyl cellulose and adjusting the dosage, the speed and time of drug release in the body can be precisely controlled, achieving once daily medication, improving efficacy, and reducing side effects.

Adhesives and thickeners: During the tablet granulation process, Hydroxypropyl methyl cellulose serves as an adhesive to uniformly bond powdered drugs together, giving the particles the necessary mechanical strength to ensure smooth compression. In liquid formulations, as a thickener, it increases viscosity, prolongs the retention time of drugs at the site of action, and improves bioavailability.

3、 Daily chemical and food industry: multifunctional improvers
Cosmetics and personal care products: used as thickeners and suspensions in products such as shampoo, shower gel, facial cleanser, etc., to give the product a comfortable consistency and texture, preventing solid particles from settling.

In lotion and face cream, it acts as an emulsion stabilizer to help oil and water coexist stably and prevent stratification. Hydroxypropyl methyl cellulose film-forming properties are also used in some special hair styling products.

Detergent: In laundry detergent and dishwashing liquid, the thickening effect of Hydroxypropyl methyl cellulose can improve the appearance quality of the product, and its anti redeposition function can also help prevent dirt from depositing on the fabric again, improving the cleaning effect.

Food industry: As a food additive, Hydroxypropyl methyl cellulose is used in food as a thickener, stabilizer, emulsifier, and water retaining agent. For example, used in baked goods to maintain moisture and extend shelf life; Simulating the taste of meat in vegetarian products; Provide a stable texture in sauces and ice cream.

Hydroxypropyl methyl cellulose's Procurement Guide

Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)

2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ:1kg

3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services

Paeonol

FAQ

Yes, we have our own factory called ” ZhiShang Industry Group “

Yes, we have GMP certificate for some products, and we can provide DMF as well.

 -Quality you require, eg. Assay, Purity, or single impurity

-Quantity you need

-Standard you want, such as USP, EP, JP etc.

Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well.

For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment. 

For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 day.

Manufacturer of Hydroxypropyl methyl cellulose

Company Info

Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
 
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.

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