PRODUCT
Zhishang Bio Ipriflavone CAS 35212-22-7
CAS:35212-22-7 | 35212-22-7 |MW:280.32 | EINECS NO：609-092-2
Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Transporta: Ocean, Land,Air, DHL，TNT
Port: Shanghai Port, Qingdao Port
Product Images & Packaging
Describe
The properties of Ipriflavone
The melting point of Ipriflavone is 115-117 ℃, and its solvent properties are as follows:
Easily soluble in chloroform or dimethylformamide
Ipriflavone is relatively soluble in acetonitrile, acetone, or ethyl acetate
Difficult to dissolve in methanol, anhydrous ethanol, or anhydrous ether
Ipriflavone is extremely insoluble in hexane and almost insoluble in water
Ipriflavone has white to yellowish white crystals or crystalline powder, odorless and tasteless. Its melting point is between 115 and 117 ℃.
The method of making Ipriflavone
Dissolve anhydrous zinc chloride in anhydrous ether, then add resorcinol. Under stirring and ice bath cooling, dry hydrogen chloride gas is introduced until saturation. Slowly add phenylacetonitrile while stirring, then introduce hydrogen chloride and let it stand.
Stir the obtained compound, anhydrous potassium carbonate, 2-bromopropane, and dimethylformamide at 110 ℃, heat them while stirring, and react. The crude product obtained was recrystallized from ethanol to obtain Ipriflavone.
The purpose of Ipriflavone
A drug developed by Takeda Pharmaceutical Industries in Japan and launched in 1988. Ipriflavone is used to improve bone loss caused by osteoporosis by inhibiting bone resorption and increasing the secretion of calcitonin, directly acting on bones.
| Product Name: | Ipriflavone |
| Synonyms: | osten;tc80;Ipriavone;osteofix;Iprflavone;IPRIFLAVONE(P);Ipriflavon;7-ISOPROPOXY-3-PHENYL-4H-1-BENZOPYRAN-4-ONE 97% |
| CAS: | 35212-22-7 |
| MF: | C18H16O3 |
| MW: | 280.32 |
| EINECS: | 609-092-2 |
| Product Categories: | APIs; |
| Mol File: | 35212-22-7.mol |
| Ipriflavone Chemical Properties |
| Melting point | 116-120 °C(lit.) |
| Boiling point | 363.04°C (rough estimate) |
| density | 1.2170 (rough estimate) |
| refractive index | 1.4700 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMF:20.0(Max Conc. mg/mL);71.35(Max Conc. mM) DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.71(Max Conc. mM) DMSO:33.11(Max Conc. mg/mL);118.11(Max Conc. mM) Ethanol:1.5(Max Conc. mg/mL);5.35(Max Conc. mM) |
| form | powder to crystal |
| color | White to Almost white |
| Merck | 14,5074 |
Ipriflavone Application
Ipriflavone is used for a variety of purposes
1. Treatment and prevention osteoporosis
Ipriflavone, a synthetic derivative of isoflavones, is widely used to treat and prevent osteoporosis. Ipriflavone has been shown to inhibit osteoclasts, reduce bone resorption and promote osteoblast differentiation. It can also increase bone density. Ipriflavone is a proven treatment for osteoporosis, which can be treated by postmenopausal woman. It also reduces the risk of fractures and has few side effects. Ipriflavone can be used with calcium and vitamin D supplements to improve bone health.
2. Relieve menopausal symptoms
Ipriflavone, which has estrogenic properties is used by menopausal woman to relieve symptoms like hot flashes and night sweats. Ipriflavone is a safer alternative to hormone replacement therapy. It’s especially suitable for women who don’t respond well to estrogen therapy. Ipriflavone is a popular menopausal ingredient because of its mild regulator effect.
3. Anti-inflammatory and antioxidant effects
Ipriflavone has antioxidant and anti-inflammatory properties. Ipriflavone has been shown to inhibit the release pro-inflammatory cytokines, and reduce chronic inflammation. Ipriflavone’s antioxidant activity helps eliminate free radicals, and reduce cellular damages caused by oxidative stresses. This may help prevent cardiovascular and neurodegenerative disease.
4. Promote collagen synthesis
Ipriflavone is known to increase the production of collagen which is essential for joint and skin function. Ipriflavone can be added to skincare products that target anti-aging to improve skin elasticity and reduce wrinkles. Ipriflavone can improve joint health by reducing symptoms of osteoarthritis and improving cartilage metabolism.
5. Potential anti-cancer adjuvant effects
Recent studies suggest that Ipriflavone can inhibit some cancers, such as breast and prostate cancer. It may be a matter of regulating estrogen receptor signaling pathways or inducing apoptosis. Ipriflavone is a natural derivative with low toxicity that may be useful in cancer adjuvant treatment. However, more clinical evidence is needed to confirm this.
6. Veterinary and Animal Health Applications
Ipriflavone has been used not only in human medicine but also in veterinary medicine to improve the health of bones in pets, such as older dogs and cats and prevent osteoporosis. Ipriflavone is also used in animal husbandry, to increase the bone strength and reduce fracture risk.
Related Products
Manufacturer of Ipriflavone
Achievements
Advantage
Service
FAQ
Advice on Shipping
Achievements
Zhishang Bio is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang Bio will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional Ipriflavone manufacturer, Zhi shang Bio has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Advantage
Zhishang Bio is a professional enterprise engaged in the research and development, production, and sales of chemical raw materials. It has a strong supply chain system and strict quality control standards to ensure the provision of high-quality products with high purity and stability to customers.
Zhishang Bio’s core strength is its independent research and design capabilities. It has advanced production equipment, testing laboratories and can customize chemical raw materials to meet the market demands. This includes pharmaceuticals, electronic, coatings and agricultural applications.
Zhishang Bio’s supply chain management is based on long-term relationships with domestic and international suppliers of high quality to guarantee a stable supply, optimize logistic systems, and achieve efficient distribution. This helps reduce the cost of customer purchases.
We adhere to international environmental standards and we also adhere to the concept that environmental protection and safety production are important. All production processes must comply with these standards in order to guarantee that our products will be green and sustainable.
With a professional technical team and comprehensive after-sales service, Zhishang Bio can provide customers with precise technical support, solve application problems, and help customers enhance product competitiveness.
We are always customer-oriented and committed to becoming a trusted chemical raw material partner.
Service
Zhishang Biography is dedicated to using clients extensive and expert service, including chemical raw material. The customers will certainly receive hassle-free, efficient and one-stop options.
1. Custom-made Supply Solutions
Zhishang Bio provides tailored services for clients in the chemical basic material sector, including special bit dimension, solvent residue control, stability optimizations and more. Clients can personalize their services to satisfy details requirements in industries such as drugs, electronic devices, and finishings.
2. Strict quality assurance
Zhishang Bio utilizes advanced screening equipment and stringent quality examination procedures, in addition to various other files, to guarantee that every batch of products is certified with international criteria such ISO GMP, REACH, and so on. Customers are also given with full quality records and conformity documents.
The supply chain is secure
Zhishang Bio has actually established lasting calculated collaborations with worldwide makers of top notch raw materials to make certain a secure supply, maximize the storage facility and logistics system, and assistance both small-scale examinations and large orders. It adjusted to the changing requirements of clients by responding flexibly to these changes.
4. Technical support
Zhishang Bio’s technical group can offer suggestions on product applications, formula optimization and analysis of industry patterns to aid clients fix technological troubles during production and boost item efficiency.
5. Efficient after-sales service
Zhishang Bio provides complete monitoring, reacts to client requests and delivers promptly. This will certainly make certain customer complete satisfaction.
Zhishang Biography intends to help consumers expand their service by providing the very best solutions and chemical resources.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.
