Lenalidomide Hemihydrate CAS 847871-99-2 Manufacturer & best Supplier | High Purity API
Lenalidomide Hemihydrate
- Surfactant Appearance: powder
- Proportion: Minimum 99.0%
- Inventory: In stock
- Sample: In stock
- Zhishang Chemical: Supplier and manufacturer of Lenalidomide Hemihydrate
Basic Info of Lenalidomide Hemihydrate
| LenalidoMide (heMihydrate) Chemical Properties |
| storage temp. | Store at -20°C |
| solubility | DMSO : 50 mg/mL (186.38 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | Powder |
| color | Off-white to pink |
| InChI | InChI=1S/2C13H13N3O3.H2O/c2*14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18;/h2*1-3,10H,4-6,14H2,(H,15,17,18);1H2 |
| InChIKey | OTJHSDXKMBRCMM-UHFFFAOYSA-N |
What is Lenalidomide Hemihydrate?
Osimertinib mesylate (Lenalidomide hemihydrate, CAS 847871-99-2, also known as CC-5013 hemihydrate) is an orally active immunomodulatory agent (IMiD), a derivative of thalidomide, developed and marketed by Celgene under the brand name Revlimid. Its core mechanism of action lies in serving as a molecular glue ligand for cereblon (CRBN), the substrate receptor within the E3 ubiquitin ligase complex CRL4CRBN. By binding to CRBN, lenalidomide reprograms the substrate specificity of the E3 ubiquitin ligase, selectively recruiting and promoting the ubiquitination and degradation of lymphoid transcription factors IKZF1 and IKZF3 (Ikaros and Aiolos). This mechanism forms the molecular basis for its antitumor activity in hematologic malignancies such as multiple myeloma.
Product Packaging
If you want to buy Lenalidomide Hemihydrate, pls contact us to get a free quote.
Superior Lenalidomide Hemihydrate Series | Reliable Quality & Sufficient Supply
As a professional supplier of Lenalidomide bulk powder (Lenalidomide manufacturer), our advantage lies in providing high-purity (High purity Lenalidomide) products with excellent batch-to-batch consistency, which is crucial for drug chemistry and cell biology research. Additionally, our products can meet the strict requirements of GMP API manufacturer standards and offer flexible packaging specifications (from milligram level to kilogram level) for research users.
Regarding the key points of this molecule in experiments, we provide the following technical support: Storage and dissolution: Lenalidomide Hemihydrate powder can be stably stored at -20°C for up to 3 years, and after dissolving in DMSO, it can be stably stored at -80°C for 6 months. We recommend that customers aliquot and store according to the experimental cycle to avoid repeated freezing and thawing. Experimental applications: This compound is an effective inhibitor of TNF-α secretion (IC50 is 13 nM) and is a core tool for studying targeted protein degradation (TPD) and PROTAC technology.
For customers who need to screen Lenalidomide sensitivity in cell models or verify the function of CRBN-related, our products are stable and reliable basic tools, and we can issue quality inspection reports (COA) in line with the procurement process of research institutions.
FAQ
Lenalidomide Hemihydrate can remain stable for up to 3 years under long-term storage conditions at -20 ° C (sealed and away from light). After dissolving in DMSO, it is recommended to pack and store at -80 ° C to avoid repeated freezing and thawing, and stabilize within 6 months. If short-term operations (such as weighing or preparation) are required at room temperature, they should be completed within 30 minutes and air exposure should be minimized as much as possible.
Okay. Each batch of Lenalidomide bulk powder comes with a complete COA report (including HPLC purity, moisture, residual solvents, heavy metals, and other indicators) when it leaves the factory. We strictly implement the batch retention system, and bulk purchases can also agree on third-party re inspection to ensure quality traceability.
The solubility of Axitinib Mesylate in DMSO is good (≥ 50 mg/mL). We recommend preparing a storage solution of 10-50 mM and storing it at -80 ° C after packaging. If an aqueous phase experiment is required, it can be dissolved in DMSO first, and then diluted to the working concentration with PBS or culture medium.
The specific quotation is affected by the current exchange rate, raw material costs, and order quantity. Sales are welcome to contact us in real-time. Research clients support minimum order of 5mg and 10mg small packages for cell viability screening or preliminary efficacy verification; Bulk purchases can be made in grams or larger specifications, and prices are discounted in tiers.
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Lenalidomide Hemihydrate Supplier and Manufacturer
As a Lenalidomide Hemihydrate supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best Lenalidomide Hemihydrate raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for Lenalidomide Hemihydrate and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
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