Product Introduction of N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine (CAS 1289942-66-0)
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine, with the CAS number 1289942-66-0, is a highly significant chemical compound in the field of pharmaceuticals and organic synthesis. This product has unique chemical properties that make it stand out among other compounds, and it has a wide range of applications in various industries. In this article, we will explore the details of N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine, including its properties, uses, applications in different fields, and the methods of its preparation.
Chemical Properties
The molecular formula of N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine is C12H13FN2O3. It consists of a phenyl ring substituted with a fluoro group and a carbonyl group connected to a methylamino group. The presence of the 2 – methylalanine moiety further contributes to its specific chemical and biological activities. The molar mass of this compound can be calculated based on its molecular formula, which helps in accurately measuring and handling it in laboratory and industrial settings.
The compound has a certain solubility profile. It may have limited solubility in water but can dissolve better in some organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO). The solubility is an important factor in its application, especially in the formulation of drugs or chemical reactions where it needs to be in a homogeneous solution. Its melting point and boiling point are also characteristic physical properties that can be determined through experimental methods. These values are crucial for processes like purification and separation during its synthesis and production.
The chemical stability of N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine is another important aspect. It should be stored under appropriate conditions to prevent degradation. Exposure to extreme temperatures, light, and moisture can potentially affect its stability and lead to the formation of impurities. Therefore, proper storage in a cool, dry, and dark place is recommended to maintain its quality over time.
Uses
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine plays a vital role in the field of drug discovery and development. It can serve as a key intermediate in the synthesis of various pharmaceutical compounds. Many drugs are designed to target specific biological pathways, and the unique structure of this compound allows it to be incorporated into drug molecules to enhance their efficacy and selectivity. For example, it can be used in the synthesis of anti – cancer drugs. Some anti – cancer agents work by inhibiting specific enzymes or receptors in cancer cells, and the presence of N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine in the drug structure can improve its binding affinity to these targets.
In addition to its use in anti – cancer drugs, it can also be involved in the development of drugs for other diseases such as neurological disorders. The compound may have an impact on neurotransmitter systems or signal transduction pathways in the nervous system. By modifying the structure of existing drug candidates with N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine, researchers can potentially create more effective drugs with fewer side effects.
Another use of this compound is in the field of chemical research. It can be used as a model compound to study chemical reactions and mechanisms. Chemists can use it to explore new synthetic routes, reaction conditions, and the reactivity of different functional groups. This research can not only expand our knowledge of organic chemistry but also lead to the development of more efficient and sustainable synthetic methods.
Applications in Various Fields
Pharmaceutical Industry
In the pharmaceutical industry, N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine is widely used in the development of new drugs. As mentioned earlier, it can be incorporated into drug molecules to improve their pharmacological properties. The compound can be used in the synthesis of small – molecule drugs, which are often easier to produce and have better bioavailability compared to large – molecule drugs such as proteins and antibodies. Pharmaceutical companies can use this compound to create drugs with improved solubility, stability, and target – binding ability.
During the drug development process, pre – clinical and clinical trials are essential steps. N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine – containing drugs need to undergo rigorous testing to ensure their safety and efficacy. These trials involve testing the drug on animals and human subjects to evaluate its pharmacokinetics, pharmacodynamics, and potential side effects. Once a drug is proven to be safe and effective, it can be approved by regulatory authorities and brought to the market.
Biotechnology
In the biotechnology field, this compound can be used in the study of biological processes at the molecular level. For example, it can be used to label or modify biomolecules such as proteins and nucleic acids. By attaching N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine to a biomolecule, researchers can track its movement and interaction within cells. This can provide valuable information about the function of the biomolecule and the underlying biological mechanisms.
Biotechnology companies can also use this compound in the development of biosensors. Biosensors are devices that can detect specific biological molecules or analytes. By incorporating N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine into the sensing element of a biosensor, the sensitivity and selectivity of the biosensor can be improved. This can have applications in areas such as medical diagnostics, environmental monitoring, and food safety.
Materials Science
In materials science, N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine can be used in the synthesis of functional materials. For example, it can be incorporated into polymers to impart specific properties to the polymers. The presence of the fluoro group and the amino – carbonyl group in the compound can enhance the hydrophobicity, chemical stability, and mechanical properties of the polymers. These functional polymers can be used in various applications such as coatings, adhesives, and membranes.
Furthermore, the compound can be used in the preparation of nanomaterials. Nanomaterials have unique properties due to their small size and high surface – to – volume ratio. By using N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine as a building block, researchers can synthesize nanomaterials with specific shapes, sizes, and surface properties. These nanomaterials can have applications in areas such as catalysis, energy storage, and drug delivery.
Preparation Methods
Traditional Organic Synthesis
One of the common methods for preparing N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine is through traditional organic synthesis. This method typically involves a series of chemical reactions starting from commercially available starting materials. For example, the synthesis may begin with the reaction of a substituted benzene derivative with appropriate reagents to introduce the fluoro and carbonyl – methylamino groups. Then, the resulting intermediate is reacted with a suitable alanine derivative to form the final product.
The reaction conditions for each step need to be carefully controlled to ensure high yield and purity of the product. This may involve controlling the temperature, reaction time, and the amount of reagents used. Catalysts may also be used to accelerate the reactions and improve the selectivity. After the synthesis, purification steps such as column chromatography or recrystallization are usually carried out to obtain the pure N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine.
Modern Synthetic Approaches
With the development of modern organic chemistry, there are also some new synthetic approaches for preparing N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine. One such approach is the use of transition – metal – catalyzed reactions. Transition – metal catalysts can enable more efficient and selective reactions, allowing for the formation of complex molecules with fewer steps. For example, palladium – catalyzed cross – coupling reactions can be used to introduce the phenyl group and other functional groups in a more controlled manner.
Another modern approach is the use of flow chemistry. Flow chemistry involves conducting chemical reactions in a continuous flow system rather than in a batch reactor. This method offers several advantages such as better heat and mass transfer, higher reaction rates, and easier scale – up. In the synthesis of N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine, flow chemistry can be used to optimize the reaction conditions and improve the overall efficiency of the synthesis process.
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