Zhishang Bio Technology|Supplier of pharmaceutical intermediates, pesticide intermediates and cosmetics raw materials

PRODUCT

Ivermectin

Zhishang Bio Ivermectin CAS 70288-86-7

CAS:70288-86-7 | Ivermectin |MW:875.09 | EINECS NO:274-536-0

Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union

Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP

Transporta: Ocean, Land,Air, DHL,TNT

Port: Shanghai Port, Qingdao Port

What exactly is ivermectin? What can it treat?

Ivermectin, a broad spectrum antiparasitic medication that treats internal parasites like worms and can be applied topically for scabies and lice.

Ivermectin is used in many animal species, including horses, cows and pigs.

The treatment can also be used to reduce microfilaments from the skin and eye tissue of humans, and last between 6-12 months. The insecticide has no effect on adults, but it can be used to treat developing larvae. It also prevents microfilaments being released from female uteri, thus preventing the transmission of microfilaments between intermediate hosts and disc tail nematodes.

Ivermectin, a semi-synthetic antibiotic, is highly effective and can kill mites and insects. It is a biological penetrant and insect nerve agent. Its mechanism of action involves interfering with neurophysiological activity of pests.

Ivermectin, a new broad-spectrum antibiotic, is highly effective and has low toxicity. It kills parasites both inside and outside of the body, including nematodes, arthropods and worms.

Ivermectin, however, is not effective against flukes, tapeworms or protozoa. The macrolide antiparasitic drug kills nematodes, arthropods, and tapeworms by increasing the release of inhibitory neurotransmitter GABA in the parasite. It also opens the glutamate-controlled Cl ion channels, increases the permeability to Cl of the nerve membrane, and blocks the transmission of nerve messages.

Ivermectin is the drug of choice for treating Onchocerca filariasis. It is also highly effective against intestinal nematodes and nematode-caused diseases.

Ivermectin’s role in the lymphatic worms is not well understood.

Product Images & Packaging

Ivermectin
Ivermectin
Ivermectin

Product Parameters

Ivermectin Chemical Properties
alpha D +71.5 ± 3° (c = 0.755 in chloroform)
RTECS IH7891500
storage temp. 2-8°C
solubility H2O: ≤1.0% KF
form powder
color White
Water Solubility 4mg/L(temperature not stated)
BCS Class4/3
Stability:Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKeyAZSNMRSAGSSBNP-XPNPUAGNSA-N
CAS DataBase Reference70288-86-7(CAS DataBase Reference)

The application of Ivermectin

application of Ivermectin

Ivermectin API has a broad spectrum and is highly effective against parasites. Its unique mechanism and broad range of applications has played an essential role in human health and livestock developments.

It is a bulk active pharmaceutical component that does not target the end consumer directly, but rather serves as an active ingredient for downstream pharmaceutical companies to produce various dosage forms, such as capsules, tablets, injections and transdermal solutions.

Ivermectin’s role is most evident in two important but distinct fields: veterinary and human public health.

Ivermectin’s main purpose in human medicine is to fight parasitic infections. Ivermectin’s mechanism targets the invertebrate nervous system and muscle cell, which makes it safe for humans and mammals.

Ivermectin is able to activate chloride channels that are glutamate-gated in parasites. Ivermectin is selectively toxic because this channel does not exist within the central nervous systems of mammals.

Ivermectin activation can cause an increase in the chloride ion flux, which causes hyperpolarization, and thus inhibits normal electrical signal transmission.

Paralysis is the end result, as it completely removes the parasite’s ability to feed, reproduce, or even move. It is then cleared out of the body by the host.

Ivermectin is the drug of choice for treating filariasis because it has such a powerful mechanism. It has controlled the spread of filariasis through large-scale distribution and donation programs. This parasitic disease has caused blindness and disability in millions of people from West Africa, Latin America and other areas. The World Health Organization’s Essential Medicines List includes it as a key antiparasitic.

Ivermectin is also used to treat scabies and other intestinal parasite infections.

Ivermectin has a huge market in veterinary medicine, economic animal husbandry and companion animals. Ivermectin has been widely used to prevent and control internal and external parasites on livestock, poultry and companion animals. Its action is directed at the majority of economic parasites including, but not limited to

Parasites found in the body include gastrointestinal roundworms (gastrointestinal nematodes), pulmonary nematodes (pulmonary nematodes), roundworms and whipworms.

External parasites include scabies mites and other external parasites such as hairy lice, ticks or maggots.

Ivermectin is a powerful parasitic treatment that can be used to treat animal parasitic infections and alleviate issues such as anemia, malnutrition, weight loss and reduced productivity. This will improve the welfare and economics of the breeding industry. Ivermectin also indirectly protects the human health by preventing zoonotic parasitic disease transmission.

Ivermectin's Procurement Guide

Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)

2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ:1kg

3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services

Paeonol

FAQ

Yes, we have our own factory called ” ZhiShang Industry Group “

Yes, we have GMP certificate for some products, and we can provide DMF as well.

 -Quality you require, eg. Assay, Purity, or single impurity

-Quantity you need

-Standard you want, such as USP, EP, JP etc.

Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well.

For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment. 

For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 day.

Related References

Manufacturer of Ivermectin

Company Info

Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
 
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.

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