PRODUCT
Zhishang Bio Pyridine-2 6-dicarboxylic acid CAS 499-83-2
CAS:499-83-2 | C7H5NO4 |MW：167.12 | EINECS NO：207-894-3
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Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Transporta: Ocean, Land,Air, DHL，TNT
Port: Shanghai Port, Qingdao Port
Description
Pyridine-2 6-dicarboxylic acid was used as a raw material to obtain the derivatives.
Pyridine-2 6-dicarboxylic Acid has a molecular mass of 167.12. The crystal is needle-shaped and insoluble in alcohol. It can be used to inhibit bovine liver glutamate.
Pyridine-2 6-dicarboxylic acid is an important pharmaceutical intermediate with a wide range of applications.
In bacterial spores is a Pyridine-2 6-dicarboxylic acid, but the content of this acid is low and it’s difficult to extract. Industrial production and use is not possible.
The multifunctional chemical building blocks of pyridine-2 6-dicarboxylic acids
The CAS number of Pyridine-2 6-dicarboxylic Acid is 499-83-2. The compound is heterocyclic and contains nitrogen. Its molecular structure is accurately described by the name: it has a central pyridine-ring, with a carboxylic-acid functional group (-COOH) attached to its 2nd and 6th Carbon atoms. The two carboxyl groups in the molecule are symmetrical, giving it unique chemical properties.
Pyridine-2 6-dicarboxylic Acid is a powdery white or off-white substance. It has an ordered molecular structure in the solid state. This is related to its purity, and predictability in synthesis.
Pyridine-2 6-dicarboxylic acids exhibit a unique characteristic in terms of their solubility: they are slightly soluble when placed in cold water but much more soluble with hot water or polar organic solvents. This solubility is the direct result of intermolecular and intramolecular forces. A strong hydrogen bond can be formed by the nitrogen atom, two carboxyl groups and other molecules. These hydrogen bonds bind molecules tightly in cold water. This results in a lower solubility. Heating breaks these bonds and increases solubility.
The two carboxylates and one nitrogen atom of Pyridine-2 6-dicarboxylic acid molecules allow them to coordinate with the metal center from multiple angles, just like a crab grasping an object using its two claws.
Metal chelates are formed by this effect. They are abnormally stable cyclic structures that have five or six members. The chelating power of Pyridine-2 6-dicarboxylic Acid is extremely high. It can form stable complexes containing over 50 metal ions including lanthanides and actinides. Most of its applications are based on the strength and specificity this interaction.
Product Images & Packaging
Product Parameters
| Pyridine-2 6-dicarboxylic acid Chemical Properties |
| Melting point | 248-250 °C (dec.)(lit.) |
| Boiling point | 295.67°C (rough estimate) |
| density | 1.5216 (rough estimate) |
| bulk density | 700kg/m3 |
| vapor pressure | <0.01 hPa (20 °C) |
| refractive index | 1.6280 (estimate) |
| Fp | 188 °C |
| storage temp. | Store below +30°C. |
| solubility | H2O: 1%, clear |
| pka | 2.16(at 25℃) |
| form | Crystalline Powder |
| color | White |
| PH | 2.0 (5g/l, H2O, 20℃) |
| Water Solubility | 5 g/L (20 ºC) |
| BRN | 131629 |
The application of Pyridine-2 6-dicarboxylic acid
Pyridine-2 6-dicarboxylic acid is more than a simple chemical. Its ability to solve complex problems in a variety of disciplines makes it important.
1. Coordination Chemistry and Supramolecular Chemistry
This is the core application area. Researchers use their excellent chelating abilities to construct complex molecules with precise geometric shapes.
Model compounds are used to simulate the active sites of metalloenzymes within biological systems. Scientists can use Pyridine-2 6-dicarboxylic acid to understand how metal ions are bonded and transferred in biomolecules.
Metal organic framework (MOF): Pyridine-2 6-dicarboxylic acid is an excellent organic linker to construct MOFs. MOFs consist of crystalline porous materials that are formed by the self-assembly or clustering of metal ions with organic ligands.
Its rigidity and the presence of multiple coordination sites enable it to produce stable MOFs with diverse structures. These materials have enormous potential for gas storage, gas separation and heterogeneous catalystalysis.
In supramolecular chemical design, Pyridine-2-6dicarboxylic acids are used to create complex assemblies that have specific functions and may be components of future nanodevices.
2. Medicine and Biochemistry
Antibacterial activity. Studies have shown Pyridine-2 6-dicarboxylic acid and some of its derivates to be inhibitory against certain bacteria and molds. Its mechanism of effect may be related its ability to chelate metal ions that are necessary for microbial development, thus depriving it of nutrients.
Drug intermediate: Pyridine-2 6-dicarboxylic acid is an important starting material for the synthesizing of more complex drug molecules. It is, for example, a key precursor in the synthesis dipyridinecarboxylic acids, which are a component of rifampicin. This drug is used to treat infections like Legionella.
Research on antioxidants: Certain studies have examined the ability of metal compounds to mimic antioxidant enzymes, such as superoxide dimutase. This may provide new ideas for developing therapeutic interventions.
3. Industrial and Materials Science
Catalyst : Pyridine-2 6-dicarboxylic acid metal complexes can be used to catalyze various organic conversion reactions including oxidation and hydrolysis. By changing the metal centre and the ligand, their activity and selectivity can easily be controlled.
Polymer modification. Pyridine-2 6-dicarboxylic acid can be added to polymer chains in order to give the material new properties, such as improved metal adsorption, increased thermal stability or certain optical properties.
Nuclear fuel reprocessing – In the nuclear industry the strong coordination ability of Pyridine-2 6-dicarboxylic acid for actinide or lanthanide element has been studied to be used in the separation process for nuclear waste treatment and nuclear energy recovery.
Pyridine-2 6-dicarboxylic acid's Procurement Guide
Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)
2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ：1kg
3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services
FAQ
It is a key compound for bacterial spore detection , metal ion chelation in analytical chemistry , and synthesis of coordination complexes . It also acts as an inert ingredient in pesticide products .
It is described as “insoluble in water” in some references , while others report solubility of approximately 5 g/L . It is soluble in ethanol, methanol, DMF, and DMSO . Our product data sheet provides detailed solubility guidance.
We supply Pyridine-2,6-dicarboxylic acid with purity >=98% . Standard packaging options are available, ranging from 25 g for research to large industrial quantities. Custom packaging can be requested.
Store at -20degC or 2-30degC for longer-term storage. Keep the container tightly closed and away from moisture. Consult your COA for batch-specific recommendations.
The material is high-purity and suitable for R&D, industrial and R&D applications. Please refer to our COA (certificate of analysis) for more detailed specifications and purity data. You can get help from our technical support team to select the best grade.
Related References
Manufacturer of Pyridine-2 6-dicarboxylic acid
Achievements
Advantage
Service
FAQ
Advice on Shipping
Achievements
Zhishang Bio is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang Bio will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional Pyridine-2 6-dicarboxylic acid manufacturer, Zhi shang Bio has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Advantage
Zhishang Bio is a professional enterprise engaged in the research and development, production, and sales of chemical raw materials. It has a strong supply chain system and strict quality control standards to ensure the provision of high-quality products with high purity and stability to customers.
Zhishang Bio’s core strength is its independent research and design capabilities. It has advanced production equipment, testing laboratories and can customize chemical raw materials to meet the market demands. This includes pharmaceuticals, electronic, coatings and agricultural applications.
Zhishang Bio’s supply chain management is based on long-term relationships with domestic and international suppliers of high quality to guarantee a stable supply, optimize logistic systems, and achieve efficient distribution. This helps reduce the cost of customer purchases.
We adhere to international environmental standards and we also adhere to the concept that environmental protection and safety production are important. All production processes must comply with these standards in order to guarantee that our products will be green and sustainable.
With a professional technical team and comprehensive after-sales service, Zhishang Bio can provide customers with precise technical support, solve application problems, and help customers enhance product competitiveness.
We are always customer-oriented and committed to becoming a trusted chemical raw material partner.
Service
Zhishang Biography is dedicated to using clients extensive and expert service, including chemical raw material. The customers will certainly receive hassle-free, efficient and one-stop options.
1. Custom-made Supply Solutions
Zhishang Bio provides tailored services for clients in the chemical basic material sector, including special bit dimension, solvent residue control, stability optimizations and more. Clients can personalize their services to satisfy details requirements in industries such as drugs, electronic devices, and finishings.
2. Strict quality assurance
Zhishang Bio utilizes advanced screening equipment and stringent quality examination procedures, in addition to various other files, to guarantee that every batch of products is certified with international criteria such ISO GMP, REACH, and so on. Customers are also given with full quality records and conformity documents.
The supply chain is secure
Zhishang Bio has actually established lasting calculated collaborations with worldwide makers of top notch raw materials to make certain a secure supply, maximize the storage facility and logistics system, and assistance both small-scale examinations and large orders. It adjusted to the changing requirements of clients by responding flexibly to these changes.
4. Technical support
Zhishang Bio’s technical group can offer suggestions on product applications, formula optimization and analysis of industry patterns to aid clients fix technological troubles during production and boost item efficiency.
5. Efficient after-sales service
Zhishang Bio provides complete monitoring, reacts to client requests and delivers promptly. This will certainly make certain customer complete satisfaction.
Zhishang Biography intends to help consumers expand their service by providing the very best solutions and chemical resources.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.
