
Wholesale Quaternium-73 CAS 15763-48-1 | Bulk Stock & Fast Delivery - Zhishang Bio
Basic Info of Quaternium-73
| Test Parameters | Specification Standard | Typical Batch Result |
|---|---|---|
| Appearance | Light yellow crystalline powder | Conforms |
| Assay (HPLC) | ≥ 95.0% | 98.40% |
| Loss on Drying | ≤ 2.0% | 0.65% |
| Residue on Ignition | ≤ 0.5% | 0.12% |
| Heavy Metals (as Pb) | ≤ 10 ppm | < 5 ppm |
| Arsenic (As) | ≤ 2 ppm | < 1 ppm |
What is Quaternium-73?
Quaternium-73 (CAS 15763-48-1) is an exceptionally efficient, quaternary ammonium salt-based active ingredient widely recognized in premium anti-acne serums, spot treatments, and soothing skincare formulations. Due to its unique cyanine structure, Quaternium-73 demonstrates superior antimicrobial performance at extremely low concentrations compared to traditional active agents.
Core Selling Point 1: Unmatched Antimicrobial Efficiency at Ultra-Low Dosage
Unlike standard anti-acne actives (such as Salicylic Acid or Benzoyl Peroxide) that require high concentration percentages (1.0%–2.0%)—often leading to skin irritation and barrier disruption—Quaternium-73 exhibits a Minimum Inhibitory Concentration (MIC) against Cutibacterium acnes (formerly Propionibacterium acnes) as low as 0.00002% (0.0002 mg/mL).
0.001% (10 ppm) addition rate delivers remarkable inhibition against acne-causing bacteria.
Significantly reduces formulation costs per batch while minimizing skin sensitization risks.
Exhibits broad-spectrum inhibition against bacteria, yeasts, and molds.
Core Selling Point 2: Dual Action — Blemish Control & Melanin Regulation
Beyond its anti-acne potency, technical studies indicate that Quaternium-73 possesses strong anti-melanin synthesis activity. It inhibits tyrosinase activity at minimal levels, preventing post-inflammatory hyperpigmentation (PIH) often caused by acne breakouts.
Helps fade dark spots and acne marks during the healing phase.
Ideal for multi-benefit formulas targeting clear, even-toned skin.
Product Packaging
If you want to buy Quaternium-73, pls contact us to get a free quote.
Superior Quaternium-73 Series | Reliable Quality & Sufficient Supply
Advanced Synthesis & Purification Technology
At Shandong Zhishang Biological Co., Ltd., we utilize a proprietary multi-step organic synthesis and precision crystallization process to produce Quaternium-73. Our dedicated production line solves common industry challenges such as batch color variation and trace iodide impurities.
HPLC Purity Control: Every batch strictly achieves ≥95.0% purity (HPLC standard), ensuring consistent efficacy in high-end cosmetic formulas.
Heavy Metal & Solvent Control: Residual solvents and trace heavy metals are rigorously controlled well below global compliance limits (EU Regulation EC No 1223/2009 & ASEAN Cosmetic Directive).
Color Consistency: Process refinement ensures stable particle sizing and batch-to-batch color stability in cosmetic bases.
Robust Production Capacity & In-Stock Reliability
As a specialized manufacturer and supplier of cosmetic raw materials and active pharmaceutical intermediates, Zhishang Bio guarantees stable global supply chain management:
Annual Production Capacity:
15 Metric Tons (MT) of cosmetic-grade Quaternium-73.
Current Stock Availability:
Over 300 kg ready-to-ship inventory maintained in our temperature-controlled Jinan warehouse.
Lead Time:
Sample dispatch within 24 hours; bulk orders shipped within 5–7 business days upon order confirmation.
Flexible Packaging options:
100g, 1kg aluminum foil bags, and custom 10kg/25kg fiber drums with double-layer PE food-grade anti-static lining.
FAQ
Quaternium-73 is slightly soluble in water, readily soluble in ethanol, polyols (such as Propylene Glycol or Butylene Glycol), and warm surfactant solutions. For optimal formulation stability:
Pre-dissolve Quaternium-73 in polyols (e.g., Butylene Glycol at 40°C–50°C) before introducing it into the water phase.
Maintain the formulation pH between 4.0 and 7.0.
Avoid prolonged exposure to direct sunlight and temperatures above 80°C during emulsion processing. Store raw materials in light-resistant containers.
While the unit price per kilogram of Quaternium-73 is higher, its effective dosage is extremely low (0.001% to 0.005%). Compared to Salicylic Acid (typically used at 1.0%–2.0%), the actual formula cost per 100g finished product is equal to or lower with Quaternium-73, while providing significantly higher mildness, faster efficacy, and lower irritation rates.
We provide full regulatory support for international cosmetic registration. Every commercial order includes:
Batch-specific Certificate of Analysis (COA)
Safety Data Sheet (SDS / MSDS according to GHS standards)
Technical Data Sheet (TDS) & Formulation Guidelines
Stability and Heavy Metal Testing Reports
To support product development for cosmetic brand owners and lab research, Zhishang Bio offers flexible purchasing options:
Sample Availability: 10g to 50g evaluation samples are available upon request.
Commercial MOQ: Starts from 1 kg.
Custom Wholesale: Tiered discount pricing is available for orders above 10 kg, 50 kg, and 100 kg.
References
The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Quaternium-73 Supplier and Manufacturer
As a Quaternium-73 supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best Quaternium-73 raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for Quaternium-73 and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
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