Spironolactone CAS 52-01-7 | >98% Purity for R&D
Spironolactone CAS 52-01-7
- Surfactant Appearance: powder
- Proportion: Minimum 99.0%
- Inventory: In stock
- Sample: In stock
- Zhishang Chemical: Supplier and manufacturer of Spironolactone
Basic Info of Spironolactone
| Spironolactone Chemical Properties |
| Melting point | 207-208 °C (lit.) |
| alpha | -37 º (c=1, CHCl3) |
| Boiling point | 504.87°C (rough estimate) |
| density | 1.1061 (rough estimate) |
| refractive index | -36 ° (C=1, CHCl3) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in ethanol (96 per cent). |
| form | Powder |
| color | White to yellow-white |
| Water Solubility | practically insoluble |
| Merck | 14,8760 |
| Henry’s Law Constant | 9.0×104 mol/(m3Pa) at 25℃, HSDB (2015) |
What is Spironolactone?
Spironolactone (CAS 52-01-7, C ₂₄ H ₃₂ O FOUR S, MW 416.57) is an artificial steroid lactone that works as a competitive aldosterone antagonist. Chemically, it is 7α-acetylthio-3-oxo-17α-pregn-4-ene-21,17- carbolactone. The substance is practically insoluble in water however soluble in natural solvents like chloroform and methanol. It appears as a white to off-white crystalline powder.
The compound has actually been FDA-approved given that 1960 and stays extensively utilized in both professional medicine and study.
Key Applications
Cardiovascular Research Study:
Utilized in researches of cardiac arrest (NYHA Class III– IV), high blood pressure, and edema monitoring.
Endocrine Research:
Checked out for key hyperaldosteronism and associated mineralocorticoid receptor studies.
Skin-related Researches:
Used in research on acne and hirsutism.
Analytical Reference Criteria:
Serves as a referral requirement for HPLC, GC, and other analytical approach advancement in pharmaceutical quality control.
Pharmaceutical R&D:
Utilized as a building block in drug discovery and metabolic researches.
Product Packaging
If you want to buy Spironolactone, pls contact us to get a free quote.
Superior Spironolactone Series | Reliable Quality & Sufficient Supply
We supply spironolactone with confirmed purity of ≥ 98% by HPLC. Every set goes through extensive quality testing covering appearance, pureness, and loss on drying out (≤ 0.5%). Each shipment includes a complete Certificate of Analysis with deducible quality specifications, ensuring batch-to-batch uniformity for your important research study or manufacturing needs.
Supply Chain Transparency
We provide extensive documents with every delivery, including COA and MSDS. The item must be kept in a completely dry, well-ventilated place listed below 30 ° C in a sealed container, safeguarded from light and oxidizing representatives.
Inventory and Adaptable Supply
We keep supply at our main storehouse. Typical packaging consists of 25g, 100g, 500g, 1kg, and 25kg drum choices. Study quantities ship within 1-2 business days. Mass orders call for 5-7 business days processing.
Technical Assistance
Our technological team supplies solution support for cardio, endocrine, and skin-related research study applications. Complete paperwork comes with every shipment.
FAQ
Spironolactone is a competitive aldosterone receptor villain. It binds to the mineralocorticoid receptor and obstructs aldosterone activity in the distal convoluted tubule, advertising salt and water discharging while keeping potassium. This device underlies its applications in heart failure, hypertension, and edema research study.
We provide ≥ 98% pureness (HPLC). Conventional packaging consists of 25g, 100g, 500g, 1kg, and 25kg drum options. Customized packaging available upon request.
Store in a sealed container in a dry, well-ventilated location listed below 30 ° C, shielded from light and oxidizing representatives. Under proper problems, the item continues to be stable for 12-24 months.
The significant active metabolites include canrenone, 7α-thiomethylspirolactone (TMS), and 6β-hydroxy-7α-thiomethylspirolactone (HTMS), with half-lives of roughly 13-16 hours. This metabolic account is relevant for pharmacokinetic researches.
Standard MOQ: 25g for research study. Stock products ship within 1-2 organization days. Bulk orders need 5-7 company days processing. Contact us for details rates and availability.
References
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Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Spironolactone Supplier and Manufacturer
As a Spironolactone supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best Spironolactone raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for Spironolactone and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
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