Zhishangbio Tofacitinib citrate CAS 540737-29-9
Tofacitinib citrate CAS 540737-29-9
CAS:540737-29-9 | C16H20N6O.C6H8O7 |MW：504.497 | EINECS NO：638-826-4
Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Transporta: Ocean, Land,Air, DHL，TNT
Port: Shanghai Port, Qingdao Port
Tofacitinib citrate Description
Product Overview
Tofacitinib Citrate is the citrate salt of tofacitinib, a compound classified as a Janus kinase (JAK) inhibitor. It is an important pharmaceutical compound with established medicinal applications. Its chemical identity and physical properties should be verified against recognized reference sources and the documentation supplied for the specific batch.
At Zhishang Bio, we support business customers seeking reliable information for pharmaceutical raw material sourcing. Contact our team to discuss Tofacitinib Citrate CAS 540737-29-9, available specifications, quality documentation, packaging options, and supply arrangements.
Whether you are evaluating a new supplier or reviewing purchasing requirements, clear product information helps your technical and procurement teams make informed sourcing decisions.
Product Images & Packaging
Tofacitinib citrate Parameters
| Product Attribute | Details |
|---|---|
| Product Name | Tofacitinib Citrate |
| CAS Number | 540737-29-9 |
| Molecular Formula | C16H20N6O · C6H8O7 |
| Molecular Weight | 504.49 g/mol |
| Assay (HPLC) | 99.0% to 101.0% (On Dried Basis) |
| Appearance | White to off-white crystalline powder |
| Regulatory Status | DMF Available / GMP Manufactured |
| Standard Packaging | 1kg/aluminum foil bag, 25kg/drum, or tailored sizes |
The application of Tofacitinib citrate
Tofacitinib Citrate: A Review of its Application
Tofacitinib, a small-molecule drug, can be taken by mouth. It is a small molecule drug that can be taken orally.
1. Rheumatoid arthritis (RA):
Tofacitinib has been used for this application ever since it was introduced. Through the JAK/STAT path, multiple pro-inflammatory cytokines are produced by RA patients and exacerbate synovitis. Tofacitinib citrate is easier for patients to administer than biologics that require injection. This increases medication adherence, and improves overall quality of living.
2. Psoriatic Arthritis (PsA).
PsA is an inflammatory joint condition caused by psoriasis. It involves a complex network of cytokines. Tofacitinib Citrate improves joint inflammation through the inhibition of cytokines, which play a major role in this disease. It also reduces finger inflammation and skin psoriasis by a significant amount.
3. Ulcerative colitis (UC):
Tofacitinib is a drug that has been used for inflammatory bowel diseases. This is a significant extension. This drug, which inhibits the JAK/STAT pathway and regulates the function and activation of lymphocytes in particular, can reduce intestinal inflammation, and promote healing of the intestinal mucosa. It has shown good therapeutic effects for UC patients.
4. Ankylosing spondylitis (AS):
Clinical trials have shown its effectiveness, even though the exact mechanism of action is not fully understood in AS patients. Tofacitinib is a new treatment option for AS. It’s especially suitable for those patients who are concerned about biologics, or prefer oral medications.
To summarize, Tofacitinib Citrate is a novel treatment option for a variety of complex immune-related diseases. It also meets the dual demands of patients, efficacy and comfort. This innovative drug is being continuously researched and developed, which gives hope that it will be used to treat more diseases in future.
Key Considerations When Sourcing Tofacitinib Citrate
1. Confirm Product Identity
When purchasing Tofacitinib Citrate, verify the product name, CAS number, molecular formula, and other applicable identification details. This helps reduce confusion between the citrate salt and the tofacitinib free base.
2. Review Quality Documentation
Quality documentation is an important part of pharmaceutical raw material procurement. Depending on availability and the intended application, buyers may request a Certificate of Analysis (COA), Safety Data Sheet (SDS), and applicable batch or analytical records.
Review the test methods, acceptance criteria, and reported results against your purchasing specifications. Document availability and regulatory suitability should be confirmed before placing an order.
3. Evaluate Supplier Communication
A dependable sourcing process requires clear communication about product specifications, sample availability, lead time, packaging, and shipping arrangements. Buyers should confirm these details before approving a purchase.
Zhishang Bio welcomes inquiries from qualified business customers seeking product information and supply quotations for Tofacitinib Citrate API.
FAQ
We provide comprehensive technical packages, including the Certificate of Analysis (COA) for every batch, Method of Analysis (MOA), Stability Data, and DMF filing details to assist your local regulatory approvals.
To support your R&D and pilot batch validation, we offer flexible MOQ options starting from 1kg. Please reach out to our sales desk to discuss your testing scope.
Our specialized crystallization technique removes specific chiral impurities and degradation products effectively, delivering an assay performance that reliably meets international standards.
Related References
Manufacturer of Tofacitinib citrate
Achievements
Advantage
Service
FAQ
Advice on Shipping
Achievements
Zhishang Bio is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang Bio will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional Tofacitinib citrate manufacturer, Zhi shang Bio has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Advantage
Zhishang Bio is a professional enterprise engaged in the research and development, production, and sales of chemical raw materials. It has a strong supply chain system and strict quality control standards to ensure the provision of high-quality products with high purity and stability to customers.
Zhishang Bio’s core strength is its independent research and design capabilities. It has advanced production equipment, testing laboratories and can customize chemical raw materials to meet the market demands. This includes pharmaceuticals, electronic, coatings and agricultural applications.
Zhishang Bio’s supply chain management is based on long-term relationships with domestic and international suppliers of high quality to guarantee a stable supply, optimize logistic systems, and achieve efficient distribution. This helps reduce the cost of customer purchases.
We adhere to international environmental standards and we also adhere to the concept that environmental protection and safety production are important. All production processes must comply with these standards in order to guarantee that our products will be green and sustainable.
With a professional technical team and comprehensive after-sales service, Zhishang Bio can provide customers with precise technical support, solve application problems, and help customers enhance product competitiveness.
We are always customer-oriented and committed to becoming a trusted chemical raw material partner.
Service
Zhishang Biography is dedicated to using clients extensive and expert service, including chemical raw material. The customers will certainly receive hassle-free, efficient and one-stop options.
1. Custom-made Supply Solutions
Zhishang Bio provides tailored services for clients in the chemical basic material sector, including special bit dimension, solvent residue control, stability optimizations and more. Clients can personalize their services to satisfy details requirements in industries such as drugs, electronic devices, and finishings.
2. Strict quality assurance
Zhishang Bio utilizes advanced screening equipment and stringent quality examination procedures, in addition to various other files, to guarantee that every batch of products is certified with international criteria such ISO GMP, REACH, and so on. Customers are also given with full quality records and conformity documents.
The supply chain is secure
Zhishang Bio has actually established lasting calculated collaborations with worldwide makers of top notch raw materials to make certain a secure supply, maximize the storage facility and logistics system, and assistance both small-scale examinations and large orders. It adjusted to the changing requirements of clients by responding flexibly to these changes.
4. Technical support
Zhishang Bio’s technical group can offer suggestions on product applications, formula optimization and analysis of industry patterns to aid clients fix technological troubles during production and boost item efficiency.
5. Efficient after-sales service
Zhishang Bio provides complete monitoring, reacts to client requests and delivers promptly. This will certainly make certain customer complete satisfaction.
Zhishang Biography intends to help consumers expand their service by providing the very best solutions and chemical resources.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.
