PRODUCT
Tranexamic Acid CAS 1197-18-8
CAS:1197-18-8 | C8H15NO2 |MW：157.21 | EINECS NO：214-818-2
Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Transporta: Ocean, Land,Air, DHL，TNT
Port: Shanghai Port, Qingdao Port
Description
Tranexamic Acid, commonly referred to by its chemical name trans-4-aminomethylcyclohexane carboxylic acid, is an essential synthetic amino acid derivative and belongs to the group of anti fibrinolytic drugs.
Tranexamic Acid has long been recognized for its hemostatic properties since being discovered by Japanese scientist Keiji Okamoto in the 1960s; and, since then, has become an essential chemical component used worldwide across medical, skincare and industrial settings.
Tranexamic Acid has the molecular formula C8H15NO2, with a molecular weight of 157.21 g/mol.
Chemical structure of this compound based on cyclohexane skeleton with two carboxyl (-COOH) and aminomethyl groups (CH2NH2) located trans on carbons 1 and 4, respectively, of cyclohexane cyclohexane.
Trans configurations are essential to biological activity; they allow molecules to efficiently bind with fibrinogen’s lysine binding site and prevent its degrading by fibrinolysis. Conversely, activity among cis isomers is significantly lower – underscoring their importance as drug functions.
Tranexamic Acid is a white crystalline powder without an unpleasant odor and slightly bitter taste.
Tranexamic Acid has a melting point between 250 deg C and 252 deg C and exhibits high thermal stability. It is easily soluble in water due to the weak acidity of its carboxyl group; slightly soluble in ethanol; insoluble in organic solvents such as ether or chloroform. At room temperature it remains stable but long-term exposure to high temperature or strong light can result in degradation.
Tranexamic Acid has an approximate pKa value between 4.3 and 10.6, which allows it to exist as zwitterionic ions at physiological pH values, making its passage through cell membranes much easier.
Product Images & Packaging
Product Parameters
| Tranexamic Acid Chemical Properties |
| Melting point | >300 °C (lit.) |
| Boiling point | 281.88°C (rough estimate) |
| density | 1.0806 (rough estimate) |
| vapor pressure | 1.72hPa at 25℃ |
| refractive index | 1.4186 (estimate) |
| storage temp. | 2-8°C |
| solubility | Freely soluble in water and in glacial acetic acid, practically insoluble in acetone and in ethanol (96 per cent). |
| form | Crystalline Powder |
| pka | pKa 4.3 (Uncertain);10.6 (Uncertain) |
| color | White |
| Water Solubility | 1g/6ml |
| Merck | 14,9569 |
| BRN | 2207452 |
| Stability: | Hygroscopic |
The application of Tranexamic Acid
1. Application in Medicine
Tranexamic Acid has long been recognized for its use as an effective form of hemostasis medication, with extensive clinical research supporting its application in medical settings.
Trauma and surgical Bleed Control:
1. Severe Trauma: Tranexamic Acid has proven itself an invaluable aid for treating severe trauma patients. A large-scale international study demonstrated how administering intravenous infusions of Tranexamic Acid immediately following trauma greatly reduces mortality from massive bleeding; particularly among traumatic brain injury sufferers. As such, its use has become standard practice at many trauma centers worldwide.
2. Surgical Procedures: Tranexamic Acid is often utilized during high-risk surgeries which carry the potential risk of blood loss to reduce transfusion needs and costs, ultimately decreasing transfusion needs and costs.
3. Cardiovascular surgery: For cardiac bypass and valve replacement surgeries, as well as routine use during these operations, hemostatic devices can help control bleeding more effectively and decrease recovery times.
4. Orthopedic surgery: Tranexamic Acid has been found effective in helping reduce intraoperative bleeding as well as postoperative drainage and swelling in total hip replacement and total knee replacement procedures, among many others.
5. Obstetric Bleeding: According to WHO, Tranexamic Acid should be seen as an essential medication in treating postpartum hemorrhage. Rapid intravenous injection of Tranexamic Acid may save lives in areas with limited medical resources; additionally it is also used to prevent it in mothers at higher-than-usual risk of it occurring.
Tranexamic Acid is an effective first-line treatment option for nonorganic menstrual disorders. By inhibiting endometrial fibrinolysis and decreasing bleeding during menstruation by up to 30%-50%, Tranexamic Acid can significantly improve quality of life while potentially delaying or postponing surgical intervention.
Tranexamic Acid can provide additional hemostatic protection during minor surgeries like tooth extraction for those living with hemophilia, as it synergizes with replacement therapy and reduces dosage requirements for factor products. Furthermore, its use applies equally well for individuals suffering from platelet dysfunction or hemophilia.
Tranexamic Acid can also help patients take prevent bleeding after tooth extraction, especially those taking anticoagulants or having a tendency for heavy bleeding that requires them to use mouthwash or topical medication as part of their regimen.
Tranexamic Acid has rapidly gained acceptance as one of the fastest-growing functional ingredients on the global skincare market since its introduction into dermatology practice.
Whitening and spot lightening essence and skin care products: multiple brands have included Tranexamic Acid as the core ingredient in their essence, face cream and facial mask products in order to reduce yellowing, brighten, reduce acne marks and even out skin tone. It may also be combined with other whitening ingredients such as vitamin C, niacinamide or retinol for synergistic effects.
High end beauty treatments: Tranexamic Acid can be administered directly into the deep layers of skin using microneedling, iontophoresis or mesodermal therapy to increase bioavailability for treating stubborn melasma and overall skin improvement.
Personal Care Products: Shampoo or haircare products claiming to improve scalp health through anti-inflammatory effects may also fall within this category; however, evidence in support of such claims remains low.
Tranexamic Acid's Procurement Guide
Procurement Guidelines
1. Sample Policy
We can provide a 2-3g free trial package (shipping fee required)
2. Batch procurement
Packaging: 25kg/bag; 220kg/barrel; Special packaging according to your needs
MOQ：1kg
3. Customized services
Concentration customization (90% -99%)
Paeonol’s outsourcing services
FAQ
Yes, we have our own factory called ” ZhiShang Industry Group “
Yes, we have GMP certificate for some products, and we can provide DMF as well.
-Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well.
For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 day.
Related References
Manufacturer of Tranexamic Acid
Achievements
Advantage
Service
FAQ
Advice on Shipping
Achievements
Zhishang Bio is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang Bio will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional Tranexamic Acid manufacturer, Zhi shang Bio has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Advantage
Zhishang Bio is a professional enterprise engaged in the research and development, production, and sales of chemical raw materials. It has a strong supply chain system and strict quality control standards to ensure the provision of high-quality products with high purity and stability to customers.
Zhishang Bio’s core strength is its independent research and design capabilities. It has advanced production equipment, testing laboratories and can customize chemical raw materials to meet the market demands. This includes pharmaceuticals, electronic, coatings and agricultural applications.
Zhishang Bio’s supply chain management is based on long-term relationships with domestic and international suppliers of high quality to guarantee a stable supply, optimize logistic systems, and achieve efficient distribution. This helps reduce the cost of customer purchases.
We adhere to international environmental standards and we also adhere to the concept that environmental protection and safety production are important. All production processes must comply with these standards in order to guarantee that our products will be green and sustainable.
With a professional technical team and comprehensive after-sales service, Zhishang Bio can provide customers with precise technical support, solve application problems, and help customers enhance product competitiveness.
We are always customer-oriented and committed to becoming a trusted chemical raw material partner.
Service
Zhishang Biography is dedicated to using clients extensive and expert service, including chemical raw material. The customers will certainly receive hassle-free, efficient and one-stop options.
1. Custom-made Supply Solutions
Zhishang Bio provides tailored services for clients in the chemical basic material sector, including special bit dimension, solvent residue control, stability optimizations and more. Clients can personalize their services to satisfy details requirements in industries such as drugs, electronic devices, and finishings.
2. Strict quality assurance
Zhishang Bio utilizes advanced screening equipment and stringent quality examination procedures, in addition to various other files, to guarantee that every batch of products is certified with international criteria such ISO GMP, REACH, and so on. Customers are also given with full quality records and conformity documents.
The supply chain is secure
Zhishang Bio has actually established lasting calculated collaborations with worldwide makers of top notch raw materials to make certain a secure supply, maximize the storage facility and logistics system, and assistance both small-scale examinations and large orders. It adjusted to the changing requirements of clients by responding flexibly to these changes.
4. Technical support
Zhishang Bio’s technical group can offer suggestions on product applications, formula optimization and analysis of industry patterns to aid clients fix technological troubles during production and boost item efficiency.
5. Efficient after-sales service
Zhishang Bio provides complete monitoring, reacts to client requests and delivers promptly. This will certainly make certain customer complete satisfaction.
Zhishang Biography intends to help consumers expand their service by providing the very best solutions and chemical resources.
FAQ
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
Advice on Shipping
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Zhishang Bio company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
The company integrates research and development, production, and trade, with a modern production base, advanced testing equipment, and an experienced technical team to ensure that products reach industry-leading levels in purity, stability, and environmental friendliness.
